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While the usual dose of chloroquine used in treatment is 10 mg/kg, toxicity begins to occur at 20 mg/kg, and death may occur at 30 mg/kg. [24] In children as little as a single tablet can be fatal. [25] [16] Treatment recommendations include early mechanical ventilation, cardiac monitoring, and activated charcoal. [24]
The drug should be given in doses between 25 mg/kg and 35 mg/kg over three days in a similar method to that used in chloroquine administration. Adverse reactions are generally similar in severity and type to that seen in chloroquine treatment. [11] In addition, bradycardia, itching, nausea, vomiting and some abdominal pain have been recorded.
Reference ranges (reference intervals) for blood tests are sets of values used by a health professional to interpret a set of medical test results from blood samples. Reference ranges for blood tests are studied within the field of clinical chemistry (also known as "clinical biochemistry", "chemical pathology" or "pure blood chemistry"), the ...
It is approved in the United States as a treatment and preventive measure against malaria. [6] The combination is considered to be more effective in treating malaria caused by Plasmodium falciparum than that caused by P. vivax, for which chloroquine is considered more effective, though in the absence of a species-specific diagnosis, the sulfadoxine-pyrimethamine combination may be indicated. [7]
On 1 April 2020, the European Medicines Agency (EMA) issued guidance that chloroquine and hydroxychloroquine are only to be used in clinical trials or emergency use programs. [ 43 ] On 9 April 2020, the National Institutes of Health began the first clinical trial to assess whether hydroxychloroquine is safe and effective to treat COVID-19.
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Primaquine is a medication used to treat and prevent malaria and to treat Pneumocystis pneumonia. [2] Specifically it is used for malaria due to Plasmodium vivax and Plasmodium ovale along with other medications and for prevention if other options cannot be used. [2] It is an alternative treatment for Pneumocystis pneumonia together with ...
It is advised to check the references for photos of reaction results. [1] Reagent testers might show the colour of the desired substance while not showing a different colour for a more dangerous additive. [2]