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Troponin. Troponin C is a protein which is part of the troponin complex. It contains four calcium-binding EF hands, although different isoforms may have fewer than four functional calcium-binding subdomains. It is a component of thin filaments, along with actin and tropomyosin. It contains an N lobe and a C lobe.
[7] Troponin activation. Troponin C (red) binds Ca2+, which stabilizes the activated state, where troponin I (yellow) is no longer bound to actin. Troponin T (blue) anchors the complex on tropomyosin. Troponin is found in both skeletal muscle and cardiac muscle, but the specific versions of troponin differ between types of muscle. The main ...
7134 21924 Ensembl ENSG00000114854 ENSMUSG00000091898 UniProt P63316 P19123 RefSeq (mRNA) NM_003280 NM_009393 RefSeq (protein) NP_003271 NP_033419 Location (UCSC) Chr 3: 52.45 – 52.45 Mb Chr 14: 30.93 – 30.93 Mb PubMed search Wikidata View/Edit Human View/Edit Mouse Troponin C, also known as TN-C or TnC, is a protein that resides in the troponin complex on actin thin filaments of striated ...
Test Sensitivity and specificity Approximate peak Description Troponin test: The most sensitive and specific test for myocardial damage. Because it has increased specificity compared with CK-MB, troponin is composed of 3 proteins- Troponin C, Cardic troponin I, and Cardiac troponin T. Troponin I especially has a high affinity for myocardial injury.
21925 Ensembl ENSG00000101470 ENSMUSG00000017300 UniProt P02585 P20801 RefSeq (mRNA) NM_003279 NM_009394 RefSeq (protein) NP_003270 NP_033420 Location (UCSC) Chr 20: 45.82 – 45.83 Mb Chr 2: 164.62 – 164.62 Mb PubMed search Wikidata View/Edit Human View/Edit Mouse Troponin C, skeletal muscle is a protein that in humans is encoded by the TNNC2 gene. Troponin (Tn), is a key protein complex in ...
AGT Video: 14-Year-Old Boy Earns Golden Buzzer With Jaw-Dropping Performance of ‘You Don’t Own Me’
Pranysqa Mishra, 9, performed Ike and Tina Turner's "River Deep —Mountain High" on "America's Got Talent," earning a Golden Buzzer from judge Heidi Klum.
A reference range is usually defined as the set of values 95 percent of the normal population falls within (that is, 95% prediction interval). [2] It is determined by collecting data from vast numbers of laboratory tests.