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Wolfram syndrome is a rare genetic disorder that causes diabetes, optic atrophy, deafness and other neurological problems. It is caused by mutations in two genes, WFS1 and WFS2, that affect the endoplasmic reticulum function.
IDDM11 (insulin-dependent diabetes mellitus 11) is one of the susceptibility genes for IDDM which locates on chromosome 14q24.3-q31. [ 2 ] [ 6 ] This loci is identified by linkage to D14S67 marker via a sibling-pair linkage analysis [ 2 ] [ 6 ] Based on the previous study, the biological behavior of IDDM11is different to HLA region genes so ...
Diabetes is a group of endocrine diseases characterized by high blood sugar levels due to insulin insufficiency or resistance. Learn about the types, causes, diagnosis, treatment, and global impact of diabetes, as well as its signs and symptoms and potential complications.
Type 2 diabetes is a form of diabetes mellitus that is characterized by high blood sugar, insulin resistance, and relative lack of insulin. It is largely preventable by staying at a normal weight, exercising regularly, and eating a healthy diet, but it can also be treated with medication, insulin, or bariatric surgery.
Insulin shock therapy or insulin coma therapy was a form of psychiatric treatment that used large doses of insulin to induce comas in patients with schizophrenia. It was introduced in 1927 by Manfred Sakel and widely used until the 1960s, but it was controversial and had serious side effects.
Learn about the acute and chronic complications of diabetes, such as diabetic ketoacidosis, hyperglycemic hyperosmolar state, neuropathy, nephropathy, and retinopathy. Find out the causes, symptoms, diagnosis, treatment, and prevention of these serious health problems.
Type 1 diabetes is an autoimmune disease that destroys insulin-producing cells in the pancreas. It causes high blood sugar levels and can lead to serious complications. Learn about the signs, causes, diagnosis, and management of type 1 diabetes.
DSM-5-TR is the latest edition of the Diagnostic and Statistical Manual of Mental Disorders, published by the American Psychiatric Association. It is used for diagnosis and treatment of mental disorders, but has also faced criticism and controversy for its reliability, validity, and cultural bias.