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Autoimmune polyendocrine syndrome type 1 ( APS-1 ), is a subtype of autoimmune polyendocrine syndrome (autoimmune polyglandular syndrome). It causes the dysfunction of multiple endocrine glands due to autoimmunity. It is a genetic disorder, inherited in autosomal recessive fashion due to a defect in the AIRE gene (autoimmune regulator), which ...
Oncology, endocrine surgery. Multiple endocrine neoplasia type 1 (MEN-1) is one of a group of disorders, the multiple endocrine neoplasias, that affect the endocrine system through development of neoplastic lesions in pituitary, parathyroid gland and pancreas. [ 1] Individuals suffering from this disorder are prone to developing multiple ...
10% (UK) [ 3] An autoimmune disease is a condition that results from an anomalous response of the adaptive immune system, wherein it mistakenly targets and attacks healthy, functioning parts of the body as if they were foreign organisms. [ 1] It is estimated that there are more than 80 recognized autoimmune diseases, with recent scientific ...
Autoimmune polyendocrine syndrome type 2, [ 7] an autosomal dominant syndrome due to multifactorial gene involvement resulting in adrenal insufficiency plus hypothyroidism and/or type 1 diabetes. Immunodysregulation polyendocrinopathy enteropathy X-linked syndrome (IPEX syndrome) is X-linked recessive due to mutation of the FOXP3 gene on the X ...
Slowly evolving immune-mediated diabetes, or latent autoimmune diabetes in adults ( LADA ), is a form of diabetes that exhibits clinical features similar to both type 1 diabetes (T1D) and type 2 diabetes (T2D), [ 3][ 4] and is sometimes referred to as type 1.5 diabetes. [ 5] It is an autoimmune form of diabetes, similar to T1D, but patients ...
The mainstay of type 1 diabetes treatment is the regular injection of insulin to manage hyperglycemia. [39] Injections of insulin via subcutaneous injection using either a syringe or an insulin pump are necessary multiple times per day, adjusting dosages to account for food intake, blood glucose levels and physical activity. [39]
Multiple Endocrine Neoplasia type 1 (MEN1) is a rare hereditary endocrine cancer syndrome characterized primarily by tumors of the parathyroid glands (95% of cases), endocrine gastroenteropancreatic (GEP) tract (30–80% of cases), and anterior pituitary (15–90% of cases). [ 19] Other endocrine and non-endocrine neoplasms including ...
Researchers from Karolinska Institutet in Stockholm, Sweden have shown that abdominal fat in obese men with type 2 diabetes has higher insulin resistance and different levels of gene expression ...
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