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Rarely, tetanus can be contracted through surgical procedures, intramuscular injections, compound fractures, and dental infections. [1] Animal bites can transmit tetanus. [1] Tetanus is often associated with rust, especially rusty nails. Although rust itself does not cause tetanus, objects that accumulate rust are often found outdoors or in ...
Their risk of infection can be significantly reduced if those who are most likely to infect them get the appropriate vaccines. [citation needed] Vaccination works by training the immune system to react promptly to an infection, warding off illness (acquired immunity). People with weak immune systems may have difficulty acquiring and retaining ...
The function of tetanolysin is unclear, although it may help C. tetani to establish infection within a wound. [6] [1] Tetanospasmin ("tetanus toxin") is a potent toxin with an estimated lethal dose less than 2.5 nanograms per kilogram of body weight, and is responsible for the symptoms of tetanus.
Tetanus vaccine, also known as tetanus toxoid (TT), is a toxoid vaccine used to prevent tetanus. [2] During childhood, five doses are recommended, with a sixth given during adolescence. [2] After three doses, almost everyone is initially immune, [2] but additional doses every ten years are recommended to maintain immunity. [3]
In immunology, passive immunity is the transfer of active humoral immunity of ready-made antibodies.Passive immunity can occur naturally, when maternal antibodies are transferred to the fetus through the placenta, and it can also be induced artificially, when high levels of antibodies specific to a pathogen or toxin (obtained from humans, horses, or other animals) are transferred to non-immune ...
Neonatal tetanus (trismus nascentium) is a form of generalised tetanus that occurs in newborns. Infants who have not acquired passive immunity from an immunized mother are at risk. It usually occurs through infection of the unhealed umbilical stump, particularly when the stump is cut with a non-sterile instrument.
Postpartum administration of the TdaP vaccine to the mother seeks to reduce the likelihood that the mother will contract disease that can be subsequently passed on the infant, albeit there will still be a two-week period prior to the protective effects of the vaccine setting in. [65] Postpartum administration is an extension of the concept of ...
Tetanus toxoid can be given in case of a suspected exposure to tetanus. In such cases, it can be given with or without tetanus immunoglobulin (also called tetanus antibodies or tetanus antitoxin [13]). It can be given as intravenous therapy or by intramuscular injection. [citation needed]