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  2. Losartan - Wikipedia

    en.wikipedia.org/wiki/Losartan

    Severe adverse effects may include angioedema, low blood pressure, and kidney problems. [4] Use during pregnancy may result in harm to the baby. [4] [1] Use is not recommended during breastfeeding. [1] It works by blocking angiotensin II. [4] Losartan was patented in 1986, and approved for medical use in the United States in 1995.

  3. Losartan/hydrochlorothiazide - Wikipedia

    en.wikipedia.org/wiki/Losartan/hydrochlorothiazide

    Serious side effects may include low blood pressure, kidney problems, allergic reactions, and electrolyte problems. [1] Use in pregnancy and breastfeeding is not recommended. [3] Losartan works by blocking the effects of angiotensin II while hydrochlorothiazide works by decreasing the ability of the kidneys to absorb electrolytes. [1]

  4. Angiotensin II receptor blocker - Wikipedia

    en.wikipedia.org/wiki/Angiotensin_II_receptor...

    Losartan, the first ARB. Angiotensin II receptor blockers (ARBs), formally angiotensin II receptor type 1 (AT 1) antagonists, [1] also known as angiotensin receptor blockers, [2] [3] angiotensin II receptor antagonists, or AT 1 receptor antagonists, are a group of pharmaceuticals that bind to and inhibit the angiotensin II receptor type 1 (AT 1) and thereby block the arteriolar contraction and ...

  5. Discovery and development of angiotensin receptor blockers

    en.wikipedia.org/wiki/Discovery_and_development...

    Losartan, valsartan, candesartan, irbesartan, telmisartan and olmesartan all contain a biphenyl-methyl group. [citation needed] Losartan is partly metabolized to its 5-carboxylic acid metabolite EXP 3174, which is a more potent AT 1 receptor antagonist than its parent compound [17] and has been a model for the continuing development of several ...

  6. Antihypertensive - Wikipedia

    en.wikipedia.org/wiki/Antihypertensive

    The choice between the drugs is to a large degree determined by the characteristics of the patient being prescribed for, the drugs' side effects, and cost. Most drugs have other uses; sometimes the presence of other symptoms can warrant the use of one particular antihypertensive. Examples include: Age can affect the choice of medications.

  7. Valsartan - Wikipedia

    en.wikipedia.org/wiki/Valsartan

    Other serious side effects may include kidney problems, low blood pressure, and angioedema. [8] Use in pregnancy may harm the baby and use when breastfeeding is not recommended. [9] It is an angiotensin II receptor antagonist and works by blocking the effects of angiotensin II. [8] Valsartan was patented in 1990, and came into medical use in ...

  8. Lisinopril - Wikipedia

    en.wikipedia.org/wiki/Lisinopril

    Common side effects include headache, dizziness, feeling tired, cough, nausea, and rash. [7] Serious side effects may include low blood pressure, liver problems, hyperkalemia (high blood potassium), and angioedema. [7] Use is not recommended during the entire duration of pregnancy as it may harm the baby. [7]

  9. Commonly prescribed drugs - Wikipedia

    en.wikipedia.org/wiki/Commonly_prescribed_drugs

    Commonly prescribed drugs are prescribed according to guidelines around the world. For instance, for ischemic heart disease, the American College of Cardiology/American Heart Association (ACC/AHA) guideline is used in the United States and the European Society of Cardiology (ESC) guideline is used in Europe.

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