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Summation, which includes both spatial summation and temporal summation, is the process that determines whether or not an action potential will be generated by the combined effects of excitatory and inhibitory signals, both from multiple simultaneous inputs (spatial summation), and from repeated inputs (temporal summation).
Temporal summation refers to successive excitatory stimuli on the same location of the postsynaptic neuron. Both types of summation are the result of adding together many excitatory potentials; the difference being whether the multiple stimuli are coming from different locations at the same time (spatial) or at different times from the same ...
Fig. 1: Spatial and temporal summation.Two EPSPs innervated in rapid succession sum to produce a larger EPSP, or an action potential in the postsynaptic cell. Coincidence detection relies on separate inputs converging on a common target.
Temporal summation occurs when graded potentials within the postsynaptic cell occur so rapidly that they build on each other before the previous ones fade. Spatial summation occurs when postsynaptic potentials from adjacent synapses on the cell occur simultaneously and add together.
Therefore, in order to achieve threshold and generate an action potential, the postsynaptic neuron has the capacity to add up all of the incoming EPSPs based on the mechanism of summation, which can occur in time and space. Temporal summation occurs when a particular synapse is stimulated at a high frequency, which causes the postsynaptic ...
Postsynaptic potentials undergo spatial and temporal summation due to their graded nature. [9] Spatial summation: When inputs are received simultaneously at nearby synapses, their postsynaptic potentials combine. Multiple excitatory inputs combine resulting in greater membrane depolarization (more positive).
Summation is the adding together of these impulses at the axon hillock. If the neuron only gets excitatory impulses, it will generate an action potential. If the neuron only gets excitatory impulses, it will generate an action potential.
The greater the value of the length constant, the further the potential will travel. A large length constant can contribute to spatial summation—the electrical addition of one potential with potentials from adjacent areas of the cell. The length constant can be defined as: = +