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Rashes typical of dermatomyositis, which include heliotrope rash, Gottron sign, and Gottron papules The fifth criterion is what differentiates dermatomyositis from polymyositis; the diagnosis is considered definite for dermatomyositis if three of items 1 through 4 are present in addition to 5, probable with any two in addition to 5, and ...
Gottron's sign is a pathognomonic cutaneous manifestation associated with dermatomyositis (DM), which is an inflammatory disorder affecting the skin and muscles. [1] The primary lesion of dermatomyositis appears as a violaceous, macular erythema with a symmetric distribution, which may progress and become poikilodermatous (atrophic with telangiectasia and pigmentary changes) and indurated (as ...
It can also be associated with underlying cancer. The main classes of idiopathic inflammatory myopathy are polymyositis (PM), dermatomyositis (DM) (including juvenile, amyopathic, and sine-dermatitis form), inclusion-body myositis (IBM), immune-mediated necrotising myopathy (IMNM), and focal autoimmune myositis. [1]
Dermatomyositis-like rashes are seen in 32–44% of those with antisynthetase syndrome. This includes heliotropic rash, Gottron papules, and lesions of the psoriasiform type that span the hand's dorsum and resemble the morphology of mechanics hands. [26] Fever is reported in 21–66% of those with antisynthetase syndrome. [27] [28]
Gottron's papules: Heinrich Adolf Gottron: rheumatology: dermatomyositis: Pathologic Basis of Disease (8th Ed), Robbins & Cotran: Scaling, erythematous eruption or dusky red patches over the knuckles, elbows and knees Gowers' sign [3] William Richard Gowers: neurology: muscular dystrophy: Graham Steell murmur: Graham Steell: cardiology: mitral ...
[19] [20] Clinically, the diagnosis of any particular skin condition is made by gathering pertinent information regarding the presenting skin lesion(s), including the location (such as arms, head, legs), symptoms (pruritus, pain), duration (acute or chronic), arrangement (solitary, generalized, annular, linear), morphology (macules, papules ...
Dermatomyositis is rare. Lyme induced dermatomyositis is rarer still but it is a form of Dermatomyositis that responds well to treatment and is "curable". Dr Steere's article has been referenced many times in articles describing successful treatment of lyme disease induced Dermatomyositis, and in at least one case where a patient's life was saved.
The three main types of idiopathic myositis (known as inflammatory myopathies) that typically test positive for autoantibodies are dermatomyositis, polymyositis, and inclusion body myositis. [4] Other autoimmune diseases, such as systemic lupus erythematosus , can also cause myositis-like symptoms.