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Lack of vitamin B12 can cause megaloblastic anemia—a condition characterized by larger than normal red blood cells in a smaller than normal amount. This causes fatigue, paleness in the skin ...
Vitamin B12 deficiency causes symptoms like fatigue, poor memory, a swollen tongue, and canker sores. Skip to main content. 24/7 Help. For premium support please call: 800-290-4726 more ways to ...
Symptoms “A B12 deficiency can cause physical and neurological symptoms, and research is also growing to support that it can also cause psychological issues as well,” says Shapiro.
Neuropsychiatric symptoms can precede hematological signs and are often the presenting manifestation of the disease. [55] Vitamin B 12 serum levels are used to detect its deficiency, but do not distinguish its causes. Vitamin B 12 levels can be falsely high or low and data for sensitivity and specificity vary widely.
[2] [7] Only some archaea and bacteria can synthesize vitamin B 12. [8] Vitamin B 12 deficiency is a widespread condition that is particularly prevalent in populations with low or no consumption of animal foods. [9] Such diets can be due to a variety of reasons, such as low socioeconomic status or personal choice (i.e., veganism, vegetarianism).
Diagnosis is not always straightforward as serum levels can be falsely high or normal. [10] Elevated methylmalonic acid levels may also indicate a deficiency. [2] Individuals with low or marginal values of vitamin B 12 in the range of 148–221 pmol/L (200–300 pg/mL) may not have classic neurological or hematological signs or symptoms. [2]
Over time, a deficiency of B12 can cause problems with balance, confusion, depression, poor memory and possibly dementia, and it can even cause permanent damage to the nervous system, Somers says.
Hypervitaminosis is a condition of abnormally high storage levels of vitamins, which can lead to various symptoms as over excitement, irritability, or even toxicity. Specific medical names of the different conditions are derived from the given vitamin involved: an excess of vitamin A , for example, is called hypervitaminosis A .