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Image of CD4 co-receptor binding to MHC (Major Histocompatibility Complex) non-polymorphic region. In molecular biology, CD4 (cluster of differentiation 4) is a glycoprotein that serves as a co-receptor for the T-cell receptor (TCR). CD4 is found on the surface of immune cells such as helper T cells, monocytes, macrophages, and dendritic cells.
Curses is designed to facilitate GUI-like functionality on a text-only device, such as a PC running in console mode, a hardware ANSI terminal, a Telnet or SSH client, or similar. Curses-based software is software whose user interface is implemented through the curses library, or a compatible library (such as ncurses ).
CD4 immunoadhesin was first developed in the mid-1990s as a potential therapeutic agent and treatment for HIV/AIDS. The protein is a fusion of the extracellular domain of the CD4 receptor and the Fc domain of human immunoglobulin G (IgG), the most abundant antibody isotype in the human body. [1]
The CD family of co-receptors are a well-studied group of extracellular receptors found in immunological cells. [4] The CD receptor family typically act as co-receptors, illustrated by the classic example of CD4 acting as a co-receptor to the T cell receptor (TCR) to bind major histocompatibility complex II (MHC-II). [5]
A version where MySQL has been replaced by PostgreSQL is called LAPP, or sometimes by keeping the original acronym, LAMP (Linux / Apache / Middleware (Perl, PHP, Python, Ruby) / PostgreSQL). [7] The LAMP bundle can be combined with many other free and open-source software packages, including: netsniff-ng for security testing and hardening
The TurnKey Linux Virtual Appliance Library is a free open-source software project which develops a range of Debian-based pre-packaged server software appliances (also called virtual appliances). Turnkey appliances can be deployed as a virtual machine (a range of hypervisors are supported), in cloud computing services such as Amazon Web ...
Gp120 binds to a CD4 and a co-receptor (CCR5 or CXCR4), found on susceptible cells such as Helper T cells and macrophages. [5] As a result, a cascade of conformational changes occurs in the gp120 and gp41 proteins. These conformational changes start with gp120 that rearranges to expose the binding sites for the coreceptors mentioned above.
In programming and software design, a binding is an application programming interface (API) that provides glue code specifically made to allow a programming language to use a foreign library or operating system service (one that is not native to that language).