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In human genetic studies, the CHLCA is useful as an anchor point for calculating single-nucleotide polymorphism (SNP) rates in human populations where chimpanzees are used as an outgroup, that is, as the extant species most genetically similar to Homo sapiens. Despite extensive research, no direct fossil evidence of the CHLCA has been discovered.
For most DNA sequences, humans and chimpanzees appear to be most closely related, but some point to a human-gorilla or chimpanzee-gorilla clade. The human genome has been sequenced, as well as the chimpanzee genome. Humans have 23 pairs of chromosomes, while chimpanzees, gorillas and orangutans have 24.
In biology and genetic genealogy, the most recent common ancestor (MRCA), also known as the last common ancestor (LCA), of a set of organisms is the most recent individual from which all the organisms of the set are descended.
For example, neutral human DNA sequences are approximately 1.2% divergent (based on substitutions) from those of their nearest genetic relative, the chimpanzee, 1.6% from gorillas, and 6.6% from baboons. [10] [11] Genetic sequence evidence thus allows inference and quantification of genetic relatedness between humans and other apes.
The gorilla–human last common ancestor (GHLCA, GLCA, or G/H LCA) is the last species that the tribes Hominini and Gorillini (i.e. the chimpanzee–human last common ancestor on one hand and gorillas on the other) share as a common ancestor. It is estimated to have lived (T GHLCA) during the late Miocene. [1] [2] [3] [4]
The genetic code (the "translation table" according to which DNA information is translated into amino acids, and hence proteins) is nearly identical for all known lifeforms, from bacteria and archaea to animals and plants. The universality of this code is generally regarded by biologists as definitive evidence in favor of universal common descent.
Along with the common chimpanzee, the bonobo is the closest extant relative to humans. [4] As the two species are not proficient swimmers, the natural formation of the Congo River (around 1.5–2 million years ago) possibly led to the isolation and speciation of the bonobo. Bonobos live south of the river, and thereby were separated from the ...
Homo heidelbergensis (in Africa also known as Homo rhodesiensis) had long been thought to be a likely candidate for the last common ancestor of the Neanderthal and modern human lineages. However, genetic evidence from the Sima de los Huesos fossils published in 2016 seems to suggest that H. heidelbergensis in its entirety should be included in ...