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Narcolepsy is a chronic neurological disorder that impairs the ability to regulate sleep–wake cycles, and specifically impacts REM (rapid eye movement) sleep. [1] The pentad symptoms of narcolepsy include excessive daytime sleepiness (EDS), sleep-related hallucinations, sleep paralysis, disturbed nocturnal sleep (DNS), and cataplexy. [1]
Patients with narcolepsy are diagnosed as either type 1 or type 2, with only the former presenting cataplexy symptoms. [57] Type 1 narcolepsy results from the loss of approximately 70,000 orexin -releasing neurons in the lateral hypothalamus , leading to significantly reduced cerebrospinal orexin levels; [ 58 ] [ 59 ] this reduction is a ...
Methylphenidate, sold under the brand names Ritalin (/ ˈ r ɪ t ə l ɪ n / RIT-ə-lin) and Concerta (/ k ə n ˈ s ɜːr t ə / kən-SUR-tə) [citation needed] among others, is a central nervous system (CNS) stimulant to treat attention deficit hyperactivity disorder (ADHD) and narcolepsy.
The movie premiered in theaters on November 22 and has raked in over $580 million at the global box office to date, also nabbing the third highest-grossing opening weekend of 2024 behind ...
At the launch of NT1 in 2005, it aired children's cartoons in the morning. [15] In the 2010s, NT1 did air live-action programming for children in the morning such as Violetta. [16] Since 8 January 2024, TFX share the children's programming block TFOU with TF1 on weekdays, airing it from 6.55 a.m. to 8.30 a.m., and until 9.30 a.m. on Wednesdays.
A month after trumpeting Dickie V is cancer-free, legendary college basketball broadcaster Dick Vitale said Wednesday he has been cleared by doctors to return to the sideline and call games for ESPN.
Israel expects the incoming Trump administration to take a hard line against Iran and its nuclear ambitions, which will create an opportunity for more peace deals with Arab neighbors, a senior ...
The full mechanism of action of sodium oxybate is poorly understood. [ 3 ] [ 7 ] GHB is a normal metabolite of GABA that interacts with the GABA B receptor and the GHB receptor . [ 3 ] It has been shown to enhance the restorativeness of sleep in part by altering sleep architecture in narcoleptic patients.
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