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Conditions that can cause saliva overproduction include: [4] Rabies; Pellagra (niacin or vitamin B 3 deficiency) [6]; Gastroesophageal reflux disease, in such cases specifically called a water brash (a loosely defined lay term), and is characterized by a sour fluid or almost tasteless saliva in the mouth [7]
Dehydration, radiotherapy involving the salivary glands, chemotherapy and several diseases can cause reduced salivation (hyposalivation), or a change in saliva consistency and hence a complaint of xerostomia. Sometimes there is no identifiable cause, and there may sometimes be a psychogenic reason for the complaint. [1]
Salivary gland dysfunction affects the flow, amount, or quality of saliva produced. A reduced salivation is termed hyposalivation.Hyposalivation often results in a dry mouth condition called xerostomia, and this can cause tooth decay due to the loss of the protective properties of saliva.
Streptococcus salivarius is a species of spherical, gram-positive, facultative anaerobic lactic acid bacteria [1] that is both catalase and oxidase negative. S. salivarius colonizes (usually in chains) the oral cavity and upper respiratory tract of humans just a few hours after birth, making further exposure to the bacteria harmless in most circumstances.
Sialolithiasis accounts for about 50% of all disease occurring in major salivary glands, and for about 66% of all obstructive salivary gland diseases. Salivary gland stones are twice as common in males as in females. The most common age range in which they occur is between 30 and 60, and they are uncommon in children. [2]
A study published in 2009 links infection with CMV to high blood pressure in mice, and suggests that the result of CMV infection of blood vessel endothelium in humans is a major cause of atherosclerosis. [51] Researchers also found that when the cells were infected with CMV, they created renin, a protein known to contribute to high blood pressure.
Oral manifestations of systematic disease are signs and symptoms of disease occurring elsewhere in the body detected in the oral cavity and oral secretions. High blood sugar can be detected by sampling saliva. [1] Saliva sampling may be a non-invasive way to detect changes in the gut microbiome and changes in systemic disease.
Cosmetic deformity is relatively minor, although symptoms may recur in up to 11-13%, of these not all require further treatment. The occurrence of recurrent symptoms is lower (4%) for subtotal parotidectomy. The choice of the surgical procedure is determined by the extent of the disease and the patient’s preference.