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William Bradley Coley (January 12, 1862 – April 16, 1936) was an American bone surgeon and cancer researcher best known for his early contributions to the study of cancer immunotherapy, specifically causing infection as a way to fight cancer, a practice used as far back as 1550 BC. [1]
Coley's toxins (also called Coley's toxin, [1] Coley's vaccine, [2] Coley vaccine, Coley's fluid or mixed bacterial vaccine) is a mixture containing toxins filtered from killed bacteria of species Streptococcus pyogenes and Serratia marcescens, named after William Coley, a surgical oncologist at the Hospital for Special Surgery who developed the mixture in the late 19th century as a treatment ...
1900 – Swedish Dr. Stenbeck cures a skin cancer with small doses of radiation [4]; 1920s – Dr. William B. Coley's immunotherapy treatment, regressed tumors in hundreds of cases, the success of Coley's Toxins attracted heavy resistance from his rival and supervisor, Dr. James Ewing, who was an ardent supporter of radiation therapy for cancer.
1893 – Use of live bacteria and bacterial lysates to treat tumors – "Coley's Toxins", based on Busch and Fehleisen experiences (William B. Coley) 1894 – Bacteriolysis (Richard Pfeiffer) 1896 – An antibacterial, heat-labile serum component is described (Jules Bordet) 1900 – Antibody formation theory (Paul Ehrlich)
1975: Cancer Research Institute William B. Coley Award for Discoveries in Basic and Tumor Immunology (honored as one of the "Founders of Tumor Immunology") 1976: Member, American Academy of Arts and Sciences; 1976: Rabbi Shai Shacknai Memorial Prize in Immunology and Cancer Research, Hebrew University of Jerusalem
James Coley was South Carolina’s wide receivers coach for all of 43 days. Coley was hired by Shane Beamer in early January to take over the Gamecocks WRs room. A longtime assistant with stops at ...
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Popular belief: Kit-Kat Reality: Kit Kat Yes, it’s true: A hyphen doesn’t separate the “kit” from “kat.” The brand even addressed the Mandela effect in a tweet from 2016, saying “the ...