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If approved, manufacturers of CBD products would be required to conduct safety tests and prove safe consumption, indicating that CBD products would not be eligible for legal commerce until at least 2021. [125] In December 2020, the European Commission concluded that CBD should not be considered as drug and can be qualified as food. [127]
Dronabinol (brand names Marinol and Syndros) is a delta-9-THC containing drug for treating HIV/AIDS-induced anorexia and chemotherapy-induced nausea and vomiting. [58] The CBD drug Epidiolex has been approved by the Food and Drug Administration for treatment of two rare and severe forms of epilepsy, [59] Dravet and Lennox-Gastaut syndromes. [60]
CBD is hydroxylated by P450 liver enzymes into 7-OH-CBD. Its metabolites are products of primarily CYP2C19 and CYP3A4 activity, with potential activity of CYP1A1, CYP1A2, CYP2C9, and CYP2D6. [69] Similar to delta-9-THC, a majority of CBD is excreted in feces and some in the urine. [57] The terminal half-life is approximately 18–32 hours. [70]
CBD oil from hemp plants (strains of the Cannabis sativa plant with no more than 0.3 percent THC) is by definition less likely to be contaminated with significant amounts of THC.
CBD commonly refers to: Cannabidiol, a drug component of cannabis; Central business district, of a city; CBD may also refer to: Biology. Ecology
The researchers noted that there is “tentative support” for using CBD to treat social anxiety; there are also case studies that suggest cannabis may help with sleep and post-traumatic stress ...
CBD, it turned out, did for Charlotte what all the pharmaceuticals in the world could not: It saved her life. ... helping kids with health needs and keeping illegal drugs from being accessible to ...
CBD is a 5-HT 1A receptor agonist, ... Canada criminalized cannabis in The Opium and Narcotic Drug Act, 1923, [216] before any reports of the use of the drug in ...