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Cocaine can cause involuntary tooth grinding, ... by long-term users, is the risk of ill effects or damage caused by the compounds used in adulteration.
Addictive behavior observed from long-term cocaine users can be due to changes in the gene expression profiles in the brain's reward circuitry. Most research has been focused on the active regions of the reward-related genes, but Maze et al. [3] focuses at what happens to the heterochromatic regions.
Animal studies in various species have found that cocaine impacts brain structure, function, and chemistry, and causes long-term changes at the molecular, cellular, and behavioral levels. [1] Animal Model Studies have shown that cocaine has the ability to cross the placenta and the blood brain barrier in the body.
Cocaine is a powerful stimulant known to make users feel energetic, cheerful, talkative, etc. In time, negative side effects include increased body temperature, irregular or rapid heart rate, high blood pressure, increased risk of heart attacks, strokes and even sudden death from cardiac arrest.
The short-term physiological effects of cocaine include [11] constricted blood vessels, dilated pupils, and increased temperature, heart rate, and blood pressure. Some users of cocaine report feelings of restlessness, irritability, and anxiety. In rare instances, sudden death can occur on the first use of cocaine or unexpectedly thereafter.
These studies have shown in particular, how the inebriated or intoxicated individual makes poorer associations between words and objects than does the sober individual. Later blackout-specific studies have indicated that alcohol specifically impairs the brain's ability to take short-term memories and experiences and transfer them to long-term ...
Cocaine increases alertness, feelings of well-being, euphoria, energy, sociability, and sexuality. The former are some of the desired effects of cocaine intoxication. Not having the normal use of mental faculties by reason of the introduction of cocaine is defined drug intoxication by the laws in America, Europe, and most of the rest of the world, and it is a serious crime in specific contexts ...
[3] [4] [5] Methamphetamine psychosis, or long-term effects of stimulant use in the brain (at the molecular level), depend upon genetics and may persist for months or years. [6] Psychosis may also result from withdrawal from stimulants, particularly when psychotic symptoms were present during use. [7]