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Biliary reflux, also called bile reflux, duodenogastroesophageal reflux (DGER) or duodenogastric reflux, is a condition that occurs when bile and/or other contents like bicarbonate and pancreatic enzymes flow upward (refluxes) from the duodenum into the stomach and esophagus.
The Saint Marys Campus houses the 148-bed Mayo Eugenio Litta Children's Hospital, offering multidisciplinary pediatric and adolescent care to infants, children, teens, and young adults aged 0–21. [ 13 ] [ 2 ] Mayo Clinic Children's Center includes providers from over 40 medical and surgical specialties.
It has also been called bile acid-induced diarrhea, cholerheic or choleretic enteropathy, bile salt diarrhea or bile salt malabsorption. It can result from malabsorption secondary to gastrointestinal disease, or be a primary disorder, associated with excessive bile acid production. Treatment with bile acid sequestrants is often effective ...
Bile salt diarrhea can also be a side-effect of gallbladder removal. [1] Bile acid sequestrants are the principal therapy for bile acid-induced diarrhea. [7] [1] Cholestyramine, colestipol and colesevelam have all been used. Doses may not need to be as high as those previously used for hyperlipidemia.
Treatment is usually with laparoscopic gallbladder removal, within 24 hours if possible. [7] [10] Taking pictures of the bile ducts during the surgery is recommended. [7] The routine use of antibiotics is controversial. [5] [11] They are recommended if surgery cannot occur in a timely manner or if the case is complicated. [5]
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The most common symptoms of GERD in adults are an acidic taste in the mouth, regurgitation, and heartburn. [16] Less common symptoms include pain with swallowing / sore throat , increased salivation (also known as water brash), nausea , [ 17 ] chest pain , coughing , and globus sensation . [ 18 ]
Primary biliary cholangitis (PBC), previously known as primary biliary cirrhosis, is an autoimmune disease of the liver. [1] [2] [3] It results from a slow, progressive destruction of the small bile ducts of the liver, causing bile and other toxins to build up in the liver, a condition called cholestasis.