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People with corticobasal degeneration (corticobasal syndrome) may develop serious complications. People with the disease may develop pneumonia, blood clots in the lungs or a dangerous response to an infection, known as sepsis. Complications often lead to death. By Mayo Clinic Staff.
What is the outlook for someone with corticobasal degeneration? A person with corticobasal degeneration has increasing difficulty taking care of themselves. People may live five to 10 years after the onset of symptoms.
Not everyone who has corticobasal degeneration has problems with memory, cognition, language, or behavior. People with CBD can live up to 6-8 years following symptom onset, sometimes longer.
A diagnosis of corticobasal degeneration (corticobasal syndrome) is made based on your symptoms, exam and testing. However, your symptoms could be due to another disease that affects the brain. Conditions that cause similar symptoms include progressive supranuclear palsy, Alzheimer's disease, Pick's disease or Creutzfeldt-Jakob disease. You may ...
The estimated prevalence of corticobasal degeneration is 4.9–7.3 cases per 100 000 population.16 The annual incidence calculated from the prevalence and life expectancy would be between 0.5 and 1 per 100 000 per year, though this is higher than the rate observed in a population based study.17 The typical age of presentation is 50s–70s and ...
As a result of these complications, the average life expectancy for someone with CBD is around 6 to 8 years from when their symptoms start. However, this is only an average and CBD is very variable. Information about you
A single study projected a prevalence of 4.9–7.3 per 100.000, based on incidence and mean survival data. However, in a cohort of 120,000, no case of CBD was described [7, 8]. Mean age at disease onset is about 64 years [4], whereas the youngest pathologically confirmed case was 43 years old [9].
A person with the disease often becomes immobile five years after symptoms emerge. Within 10 years, pneumonia or other bacterial infections may lead to life-threatening complications.
CBD usually progresses gradually over the course of six to eight years. Learn more about corticobasal degeneration (CBD), a progressive disorder which can lead to nerve cell loss and atrophy over the course of six to eight years.
CBD is also referred to as an atypical parkinsonian syndrome based on distinct yet overlapping features with Parkinson disease; other atypical parkinsonian disorders include PSP and multiple system atrophy. This topic will review the clinical features, pathology, diagnosis, and management of CBD.