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  2. WHO Model List of Essential Medicines - Wikipedia

    en.wikipedia.org/wiki/WHO_Model_List_of...

    The first list was published in 1977 and included 208 medications. [8] [2] [9] The WHO updates the list every two years. [10] There are 306 medications in the 14th list in 2005, [11] 410 in the 19th list in 2015, [10] 433 in the 20th list in 2017, [12] [13] 460 in the 21st list in 2019, [14] [15] [16] and 479 in the 22nd list in 2021.

  3. Nintedanib - Wikipedia

    en.wikipedia.org/wiki/Nintedanib

    In March 2020, it was approved for use in the United States to treat chronic fibrosing (scarring) interstitial lung diseases (ILD) with a progressive phenotype (trait). [6] It is the first treatment for this group of fibrosing lung diseases that worsen over time that was approved by the U.S. Food and Drug Administration (FDA).

  4. List of largest selling pharmaceutical products - Wikipedia

    en.wikipedia.org/wiki/List_of_largest_selling...

    Drug Trade name Type Main indications Company Sales (USD millions/year) ∆ vs 2014 1 Adalimumab: Humira Biologic Rheumatoid arthritis: AbbVie Inc. 14,012 1,469 2 Ledipasvir/sofosbuvir: Harvoni Small molecule Hepatitis C: Gilead Sciences: 13,864 11,737 3 Etanercept: Enbrel Biologic Rheumatoid arthritis: Amgen. Pfizer. 8,697 4,009 4 Infliximab ...

  5. Essential medicines - Wikipedia

    en.wikipedia.org/wiki/Essential_medicines

    While the EML (Essential Medicine List) is intended for the population as a whole, the EMLc (Essential Medicine List for Children) is intended for children up to 12 years old. [25] The first edition contained 450 formulations of 200 different medications [ 7 ] and the 2023 list contains 361 medications. [ 23 ]

  6. Top aging expert says these 4 FDA-approved drugs hold promise ...

    www.aol.com/finance/global-aging-doctor-says-4...

    One analysis found people using bisphosphonates were 15% less likely to die than nonusers after a 2.8 year follow up. Metformin Metformin, which has been around for 60 years, is the most ...

  7. List of drugs granted breakthrough therapy designation

    en.wikipedia.org/wiki/List_of_drugs_granted...

    Amgen. non-small cell lung cancer with KRAS G12C mutation. Avapritinib. Blueprint Medicines Corp. granted for two indications: mast cell leukemia and advanced systemic mastocytosis. Belumosudil. Kadmon Pharmaceuticals. chronic graft-versus-host disease. Pembrolizumab.

  8. Prescription drug prices in the United States - Wikipedia

    en.wikipedia.org/wiki/Prescription_drug_prices...

    Prescription drug list prices in the United States continually are among the highest in the world. [1] [2] The high cost of prescription drugs became a major topic of discussion in the 21st century, leading up to the American health care reform debate of 2009, and received renewed attention in 2015.

  9. United States drug overdose death rates and totals over time

    en.wikipedia.org/wiki/United_States_drug...

    A two milligram dose of fentanyl powder (on pencil tip) is a lethal amount for most people. [ 3 ] The United States Centers for Disease Control and Prevention (CDC) has data on drug overdose death rates and totals. Around 1,106,900 US residents died from drug overdoses from 1968 to 2020. Around 932,400 died from 1999 through 2020.