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The causes of schizophrenia that underlie the development of schizophrenia, a psychiatric disorder, are complex and not clearly understood.A number of hypotheses including the dopamine hypothesis, and the glutamate hypothesis have been put forward in an attempt to explain the link between altered brain function and the symptoms and development of schizophrenia.
A genetic predisposition on its own, without interacting environmental factors, will not give rise to the development of schizophrenia. [81] [82] The genetic component means that prenatal brain development is disturbed, and environmental influence affects the postnatal development of the brain. [83]
Schizophrenia is a debilitating and often misunderstood disorder that affects up to 1% of the world's population. [1] Although schizophrenia is a heavily studied disorder, it has remained largely impervious to scientific understanding; epigenetics offers a new avenue for research, understanding, and treatment.
Polimeni and Reiss' group selection hypothesis of schizophrenia emphasizes the shamanism, or shaman-like behaviors, arguing that there is a need to consider the genetic root of such behaviors. [2] One related hypothesis argues that schizophrenia helps maintain charismatic leaders who utilize symptoms, such as paranoia and delusions, to create ...
Evidence suggests that it is the interaction between genes and the environment may be associated with the development of schizophrenia. [2] This is a complex process involving multiple environmental factors that have influence on a range of developmental periods that interact with a genetic susceptibility. [7]
All four of the sisters developed schizophrenia by the age of 24. [2] There was a history of mental illness in Mr. Genain's family that might have been an example of genetics being linked with mental illness or it may have just been a dysfunctional and abusive family free from a specific genetic component. Mr.
If possible to test for schizophrenia before the symptoms develop, proactive interventions could be developed, or even preventative treatments. [7] In one study, 100% of patients with bipolar disorder indicated that they would probably take a genetic test to determine they were carrying a gene associated with the disorder, if such a test ...
In the first half of the 20th century schizophrenia was considered to be a hereditary defect, and affected people were subject to eugenics in many countries. Hundreds of thousands were sterilized, with or without consent—the majority in Nazi Germany, the United States, and Scandinavian countries.
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