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Acceptable daily intake or ADI is a measure of the amount of a specific substance (originally applied for a food additive, later also for a residue of a veterinary drug or pesticide) in food or drinking water that can be ingested (orally) daily over a lifetime without an appreciable health risk. [1]
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A 12-US-fluid-ounce (350 ml; 12 imp fl oz) can of diet soda contains 0.18 grams (0.0063 oz) of aspartame, and, for a 75-kilogram (165 lb) adult, it takes approximately 21 cans of diet soda daily to consume the 3.7 grams (0.13 oz) of aspartame that would surpass the FDA's 50 mg/kg of body weight ADI of aspartame from diet soda alone.
In the United States, six high-intensity sugar substitutes have been approved for use: aspartame, sucralose, neotame, acesulfame potassium (Ace-K), saccharin and advantame. [3] Food additives must be approved by the FDA, [ 3 ] and sweeteners must be proven as safe via submission by a manufacturer of a GRAS document. [ 44 ]
The only exception is aspartame, which provides the same amount of calories as sugar per gram but is typically used in small quantities. Sugar alcohols. Sugar alcohols include erythritol, xylitol ...
The World Health Organization’s findings on the non-sugar sweetener aspartame as “possibly carcinogenic to humans,” emphasize the need for healthier diets overall and greater research around ...
Of these 59 (70%) had symptoms related to intake of food, 62% limited or excluded food items from the diet. Tests were performed for food allergy and malabsorption, but not for intolerance. There were no associations between the tests for food allergy and malabsorption and perceived food intolerance, among those with IBS.
Decades after aspartame was approved for use in the United States, the sweetener’s safety is getting another look by global health bodies assessing its potential links to cancer.