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The male hormone, testosterone, is produced in limited quantities following treatment with Zeuterin, but after two years, testosterone production is similar to that in untreated dogs. [1] The continuing presence of testosterone means that, unlike surgical castration, chemical castration does not remove the risk of testosterone-associated ...
As oil solutions by intramuscular injection, the elimination half-lives of testosterone esters are 0.8 days for testosterone propionate, 4.5 days for testosterone enanthate, 20.9 days (in tea seed oil) and 33.9 days (in caster oil) for testosterone undecanoate, and 29.5 days for testosterone buciclate.
Sublingual testosterone can also be made by some compounding pharmacies. Cost for Striant is greater than other formulations (US$180–210 /month). Testosterone is absorbed through the oral mucosa and avoids the first-pass metabolism in the liver which is the cause of many of the adverse effects of oral testosterone undecanoate.
Testosterone replacement therapy works by increasing the amount of testosterone in your system. You’ll take synthetic testosterone to make up for low levels of the natural hormone in your body.
The first long-acting (depot) injections were antipsychotics fluphenazine and haloperidol. [2] The concept of a depot injection arose before 1950, and originally was used to describe antibiotic injections that lasted longer to allow for less frequent administration.
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[20] [21] [22] GonaCon has been studied in male and female dogs and cats but does not provide long-acting suppression of fertility in these species. In dogs in particular, injection site reactions preclude use of the EPA approved formulation. [23] [24] Zona pellucida vaccines are targeted at females and do not suppress fertility in dogs or cats ...
Testosterone cypionate is a testosterone ester and a long-lasting prodrug of testosterone in the body. [7] [2] [3] Because of this, it is considered to be a natural and bioidentical form of testosterone. [14] Testosterone cypionate was introduced for medical use in 1951.