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Mendelian inheritance (also known as Mendelism) is a type of biological inheritance following the principles originally proposed by Gregor Mendel in 1865 and 1866, re-discovered in 1900 by Hugo de Vries and Carl Correns, and later popularized by William Bateson. [1] These principles were initially controversial.
Experiments on Plant Hybridization" (German: Versuche über Pflanzen-Hybriden) is a seminal paper written in 1865 and published in 1866 [1] [2] by Gregor Mendel, an Augustinian friar considered to be the founder of modern genetics. The paper was the result after years spent studying genetic traits in Pisum sativum, the pea plant.
Autosomal dominant A 50/50 chance of inheritance. Sickle-cell disease is inherited in the autosomal recessive pattern. When both parents have sickle-cell trait (carrier), a child has a 25% chance of sickle-cell disease (red icon), 25% do not carry any sickle-cell alleles (blue icon), and 50% have the heterozygous (carrier) condition. [1]
The combination, in the 1930s and 1940s, of Mendelian genetics with Darwin's theory of natural selection resulted in the modern synthesis of evolutionary biology. [50] [51] In the Soviet Union and China, Mendelian genetics was rejected in favor of Lamarckism, leading to imprisonment and even execution of Mendelian geneticists (see Lysenkoism).
This is an accepted version of this page This is the latest accepted revision, reviewed on 27 February 2025. Science of genes, heredity, and variation in living organisms This article is about the general scientific term. For the scientific journal, see Genetics (journal). For a more accessible and less technical introduction to this topic, see Introduction to genetics. For the Meghan Trainor ...
The existence of discrete inheritable units was first suggested by Gregor Mendel (1822–1884). [30] From 1857 to 1864, in Brno , Austrian Empire (today's Czech Republic), he studied inheritance patterns in 8000 common edible pea plants , tracking distinct traits from parent to offspring.
In the period 1961 – 1967, through work in several different labs, the nature of the genetic code was determined (e.g. [31]). In 1972, Walter Fiers and his team at the University of Ghent were the first to determine the sequence of a gene: the gene for bacteriophage MS2 coat protein. [ 32 ]
The modern synthesis [a] was the early 20th-century synthesis of Charles Darwin's theory of evolution and Gregor Mendel's ideas on heredity into a joint mathematical framework. Julian Huxley coined the term in his 1942 book, Evolution: The Modern Synthesis .