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A lysosome (/ ˈ l aɪ s ə ˌ s oʊ m /) is a single membrane-bound organelle found in many animal cells. [1] [2] They are spherical vesicles that contain hydrolytic enzymes that digest many kinds of biomolecules. A lysosome has a specific composition, of both its membrane proteins and its lumenal proteins.
Chromosome 1 is the designation for the largest human chromosome. Humans have two copies of chromosome 1, as they do with all of the autosomes , which are the non- sex chromosomes . Chromosome 1 spans about 249 million nucleotide base pairs , which are the basic units of information for DNA . [ 4 ]
The list of organisms by chromosome count describes ploidy or numbers of chromosomes in the cells of various plants, animals, protists, and other living organisms.This number, along with the visual appearance of the chromosome, is known as the karyotype, [1] [2] [3] and can be found by looking at the chromosomes through a microscope.
Tripeptidyl-peptidase 1, also known as Lysosomal pepstatin-insensitive protease, is an enzyme that in humans is encoded by the TPP1 gene, also known as CLN2. [ 5 ] [ 6 ] TPP1 should not be confused with the TPP1 shelterin protein which protects telomeres and is encoded by the ACD gene . [ 7 ]
66508 Ensembl ENSG00000149357 ENSMUSG00000030842 UniProt Q6IAA8 Q9CQ22 RefSeq (mRNA) NM_017907 NM_025605 RefSeq (protein) NP_060377 NP_079881 Location (UCSC) Chr 11: 72.09 – 72.1 Mb Chr 7: 101.56 – 101.58 Mb PubMed search Wikidata View/Edit Human View/Edit Mouse Late endosomal / lysosomal adaptor, MAPK and MTOR activator 1 is a protein that in humans is encoded by the LAMTOR1 gene ...
2647 14533 Ensembl ENSG00000135441 ENSMUSG00000090247 UniProt P78537 O55102 RefSeq (mRNA) NM_001487 NM_015740 RefSeq (protein) NP_001478 NP_056555 Location (UCSC) Chr 12: 55.72 – 55.72 Mb Chr 10: 128.75 – 128.76 Mb PubMed search Wikidata View/Edit Human View/Edit Mouse Biogenesis of lysosome-related organelles complex 1 subunit 1 is a protein that in humans is encoded by the BLOC1S1 gene ...
The distinct chromosome territories of chromosome 2 (red) and chromosome 9 (green) are stained with fluorescent in situ hybridization. The cell nucleus contains the majority of the cell's genetic material in the form of multiple linear DNA molecules organized into structures called chromosomes. Each human cell contains roughly two meters of DNA.
This gene is a member of the Sec-1 domain family, and encodes the human ortholog of rat Vps33b which is homologous to the yeast class C Vps33 protein. The mammalian class C Vps proteins are predominantly associated with late endosomes/lysosomes, and like their yeast counterparts, may mediate vesicle trafficking steps in the endosome/lysosome ...