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Head & Shoulders (H&S) is an American brand of anti-dandruff and non-dandruff shampoo produced by parent company Procter & Gamble. The active anti-fungal ingredient in Head & Shoulders is piroctone olamine [ 2 ] or zinc pyrithione , [ 3 ] with some "clinical strength" varieties also containing selenium disulfide .
Head & Shoulders is a classic for a reason. A tried and true anti-dandruff shampoo, people with dry, itchy scalps rave about it. This particular product in the head and shoulders range is enriched ...
Selsun Blue is an over-the-counter brand of dandruff shampoo now owned by Sanofi.First made by Abbott Laboratories, the brand was bought by Chattem in 2002. Chattem was acquired by Sanofi in 2010, although in some markets, it is sold by Rohto Pharmaceutical instead.
Dandruff is a skin condition of the scalp. [1] Symptoms include flaking and sometimes mild itchiness. [1] [2] It can result in social or self-esteem problems. [6]A more severe form of the condition, which includes inflammation of the skin, is known as seborrhoeic dermatitis.
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Its antifungal effect is thought to derive from its ability to disrupt membrane transport by blocking the proton pump that energizes the transport mechanism. [16] A study from 2011 showed that antifungal effects of Zinc pyrithione work by copper toxicity mechanism that targets critical iron–sulphur proteins. [17]
Caspofungin (INN; [1] [4] brand name Cancidas) is a lipopeptide antifungal drug from Merck & Co., Inc.. [5] It is a member of a class of antifungals termed the echinocandins. [medical citation needed] It works by inhibiting the enzyme (1→3)-β-D-glucan synthase and thereby disturbing the integrity of the fungal cell wall.
Climbazole is a topical antifungal agent commonly used in the treatment of human fungal skin infections such as dandruff, seborrhoeic dermatitis and eczema. [2] Climbazole has shown a high in vitro and in vivo efficacy against Malassezia spp. that appear to play an important role in the pathogenesis of dandruff. [2]
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