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When multiple EPSPs occur on a single patch of postsynaptic membrane, their combined effect is the sum of the individual EPSPs. Larger EPSPs result in greater membrane depolarization and thus increase the likelihood that the postsynaptic cell reaches the threshold for firing an action potential.
[1] [2] Infantile apnea occurs in children under the age of one and it is more common in premature infants. [3] Symptoms of infantile apnea occur most frequently during the rapid eye movement (REM) stage of sleep. [4] The nature and severity of breathing problems in patients can be detected in a sleep study called a polysomnography which ...
It usually occurs when the infant is sleeping deeply, but may occur with light sleep or even when awake. Studies have shown that 78% of healthy full-term infants experience episodes of periodic breathing in the first two weeks of life, which typically resolves in the first six months of life.
Less common than obstructive sleep apnea is another form called central sleep apnea, in which breathing muscles aren’t active enough. For these patients, CPAP may not help as much. For these ...
Breath-holding spells occur in approximately 5% of the population with equal distribution between males and females. They are most common in children between 6 and 18 months and usually not present after 5 years of age. They are unusual before 6 months of age. A positive family history can be elicited in 25% of cases.
Untreated sleep apnea can lead to serious health conditions. Moderate to severe sleep apnea can increase your risk of: High blood pressure. Heart failure. Cardiovascular disease. Stroke. Fatty ...
Transient tachypnea of the newborn occurs in approximately 1 in 100 preterm infants and 3.6–5.7 per 1000 term infants. It is most common in infants born by caesarian section without a trial of labor after 35 weeks of gestation. Male infants and infants with an umbilical cord prolapse or perinatal asphyxia are at higher risk.
EPSPs and IPSPs are transient changes in the membrane potential. These changes in membrane potential occur at the postsynaptic membrane located on the dendrites or cell body of a neuron, specifically at the synapse where it receives signals from a presynaptic neuron. [7]