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The orbitofrontal cortex (OFC) is a prefrontal cortex region in the frontal lobes of the brain which is involved in the cognitive process of decision-making.In non-human primates it consists of the association cortex areas Brodmann area 11, 12 and 13; in humans it consists of Brodmann area 10, 11 and 47.
Brodmann area 11, or BA11, is part of the frontal cortex in the human brain. BA11 is the part of the orbitofrontal cortex that covers the medial portion of the ventral surface of the frontal lobe. Prefrontal area 11 of Brodmann-1909 is a subdivision of the frontal lobe in the human defined on the basis of cytoarchitecture. Defined and ...
The uncinate fasciculus is a white matter association tract in the human brain that connects parts of the limbic system such as the temporal pole, anterior parahippocampus, and amygdala in the temporal lobe with inferior portions of the frontal lobe such as the orbitofrontal cortex.
Simplified diagram of frontal cortex to striatum to thalamus pathways. There are five defined frontostriatal circuits: motor and oculomotor circuits originating in the frontal eye fields are involved in motor functions; while dorsolateral prefrontal, orbital frontal, and anterior cingulate circuits are involved in executive functions, social behavior and motivational states. [2]
The orbitofrontal cortex, amygdala, hippocampus, thalamus, and olfactory bulb have many interconnections directly and indirectly through the cortices of the primary olfactory cortex. These connections are indicative of the association between the olfactory bulb and higher areas of processing, specifically those related to emotion and memory.
Orbitofrontal cortex: a region in the frontal lobe involved in the process of decision-making; Piriform cortex: part of the olfactory system; Entorhinal cortex: related to memory and associative components; Fornix: a white matter structure connecting the hippocampus with other brain structures, particularly the mammillary bodies and septal nuclei
The dorsolateral prefrontal cortex (DLPFC or DL-PFC) is an area in the prefrontal cortex of the primate brain. It is one of the most recently derived parts of the human brain. It undergoes a prolonged period of maturation which lasts into adulthood. [1] The DLPFC is not an anatomical structure, but rather a functional one.
Area 13 is located in the posterior part of the Orbitofrontal cortex, and can be subdivided into areas 13a, 13b, 13m, 13l.Area 13a is anterior to the junction of olfactory tract and area 13b occupies a region just anterior to 13a along the olfactory sulcus.