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Eukaryotes initiate DNA replication at multiple points in the chromosome, so replication forks meet and terminate at many points in the chromosome. Because eukaryotes have linear chromosomes, DNA replication is unable to reach the very end of the chromosomes. Due to this problem, DNA is lost in each replication cycle from the end of the chromosome.
Rolling circle replication (RCR) is a process of unidirectional nucleic acid replication that can rapidly synthesize multiple copies of circular molecules of DNA or RNA, such as plasmids, the genomes of bacteriophages, and the circular RNA genome of viroids. Some eukaryotic viruses also replicate their DNA or RNA via the rolling circle mechanism.
The process of DNA replication is a fundamental process used by all living organisms as it is the basis for biological inheritance. Reason same reasons given in Cell membrane (diagrammatic) Articles this image appears in DNA replication, DNA, Replication fork Creator Mariana Ruiz. Support as nominator--Alokprasad84 08:17, 12 June 2008 (UTC)
Required for initiation and elongation steps of DNA replication. A part of the Mcm2-7 helicase complex. Required after pre-RC step for loading of various proteins for initiation and elongation. Cdc45-Mcm-GINS (CMG) complex: Functional DNA helicase in eukaryotic cells Cdc6: Required for assembly of Mcm2-7 complex at ORC, in conjunction with Cdt1 .
This image is a derivative work of the following images: File:DNA_replication_en.svg licensed with PD-user . 2009-06-01T14:09:19Z Bibi Saint-Pol 691x336 (113021 Bytes) {{Information |Description= {{en|DNA replication or DNA synthesis is the process of copying a double-stranded DNA molecule.
The eukaryotic cell cycle consists of four distinct phases: G 1 phase, S phase (synthesis), G 2 phase (collectively known as interphase) and M phase (mitosis and cytokinesis). M phase is itself composed of two tightly coupled processes: mitosis, in which the cell's nucleus divides, and cytokinesis, in which the cell's cytoplasm and cell membrane divides forming two daughter cells.
DNA gyrase's preliminary role is to introduce negative super coils into DNA, thereby relaxing positive supercoils that form during DNA replication. Topoisomerase IV also relaxes positive supercoils, therefore, DNA Gyrase and topoisomerase IV play an almost identical role in removing the positive supercoils ahead of a translocating DNA ...
Asymmetry in the synthesis of leading and lagging strands. Okazaki fragments are short sequences of DNA nucleotides (approximately 150 to 200 base pairs long in eukaryotes) which are synthesized discontinuously and later linked together by the enzyme DNA ligase to create the lagging strand during DNA replication. [1]