Search results
Results from the WOW.Com Content Network
Paraneoplastic pemphigus (PNP) is an autoimmune disorder stemming from an underlying tumor. It is hypothesized that antigens associated with the tumor trigger an immune response resulting in blistering of the skin and mucous membranes .
Pemphigus erythematosus (Senear-Usher Syndrome) is a rare form of pemphigus with features of pemphigus foliaceus and lupus erythematosus. [ 1 ] [ 2 ] It was first described by Francis Senear and Barney Usher at the University of Illinois College of Medicine in 1926. [ 3 ]
The cause of the disease is a haploinsufficiency of the enzyme ATP2C1; [7] the ATP2C1 gene is located on chromosome 3, which encodes the protein hSPCA1.A mutation on one copy of the gene causes only half of this necessary protein to be made and the cells of the skin do not adhere together properly due to malformation of intercellular desmosomes, causing acantholysis, blisters and rashes.
Pseudoexfoliation syndrome is considered to be the most common of identifiable causes of glaucoma. [5] If PEX is diagnosed without glaucoma, there is a high risk of a patient subsequently developing glaucoma. [3] Country and region. Prevalence of PEX varies by geography.
“Analyzing vascular fingerprints on the retina across populations can help identify trends and risk factors associated with stroke.” Seventeen of the 29 indicators are density indicators.
Recurrent corneal erosion syndrome: Anatomy (normal) cornea: Specialty: Ophthalmology: Symptoms: Pain, photophobia: Usual onset: Usually at night or around upon first awakening: Duration: Potentially chronic: Causes: Weak attachments of the basal epithelium and basement membrane with the underlying Bowman's layer: Risk factors
Exfoliation syndrome: Exfoliation syndrome is a classic cause of secondary open-angle glaucoma, a common symptom of exfoliation syndrome is a cloudy layer on the anterior lens capsule. [ 2 ] Aphakic and pseudophakic glaucoma: Aphakic glaucoma is a common side-effect of cataract surgery which causes an increase in IOP.
The tissue is skin from a patient with Pemphigus vulgaris. Note the intercellular IgG deposits in the epidermis and the early intraepidermal vesicle caused by acantholysis. Pemphigus (/ ˈ p ɛ m f ɪ ɡ ə s / or / p ɛ m ˈ f aɪ ɡ ə s /) is a rare group of blistering autoimmune diseases that affect the skin and mucous membranes. [1]