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Armodafinil, sold under the brand name Nuvigil, is a wakefulness-promoting medication which is used to treat excessive daytime sleepiness associated with obstructive sleep apnea, narcolepsy, and shift work disorder. [1] It is also used off-label for certain other indications. [10] The drug is taken by mouth. [1]
Kidney failure, rapidly stopping blood pressure medication, pheochromocytoma, taking monoamine oxidase inhibitor with foods containing tyramine, eclampsia [2] Diagnostic method: Blood pressure > 200/130 mmHg and general brain dysfunction [1] Differential diagnosis: Uremic encephalopathy, stroke (ischemic or bleeding), hydrocephalus, cocaine ...
Modafinil can stimulate the release of norepinephrine and epinephrine, hormones that activate the sympathetic nervous system. This can cause vasoconstriction, which is the narrowing of blood vessels, and increase the heart's workload, which is not desired in people with pre-existing heart conditions. In particular, modafinil can worsen the ...
Antihypertensive therapy seeks to prevent the complications of high blood pressure, such as stroke, heart failure, kidney failure and myocardial infarction. Evidence suggests that a reduction of blood pressure by 5 mmHg can decrease the risk of stroke by 34% and of ischaemic heart disease by 21%.
Indapamide has been shown to reduce stroke rates in people with high blood pressure. [ 7 ] [ 11 ] [ 12 ] Studies have shown that the blood pressure lowering effects of indapamide in combination with perindopril reduce the rate of stroke in high risk patients (those with a history of high blood pressure, stroke or type two diabetes).
A eugeroic, or eugregoric, is a type of drug that increases wakefulness. [1] [2] [3] [4] The term has been used inconsistently and in multiple ways in the scientific ...
The most common presentation of cerebrovascular disease is an ischemic stroke or mini-stroke and sometimes a hemorrhagic stroke. [2] Hypertension (high blood pressure) is the most important contributing risk factor for stroke and cerebrovascular diseases as it can change the structure of blood vessels and result in atherosclerosis. [5]
A medication overuse headache (MOH), also known as a rebound headache, usually occurs when painkillers are taken frequently to relieve headaches. [1] These cases are often referred to as painkiller headaches. [2] Rebound headaches frequently occur daily, can be very painful and are a common cause of chronic daily headache.
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