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Histoplasmosis is a fungal infection caused by Histoplasma capsulatum. [ 2 ] [ 3 ] Symptoms of this infection vary greatly, but the disease affects primarily the lungs . [ 4 ] Occasionally, other organs are affected; called disseminated histoplasmosis, it can be fatal if left untreated.
Histoplasma capsulatum is a species of dimorphic fungus.Its sexual form is called Ajellomyces capsulatus.It can cause pulmonary and disseminated histoplasmosis.. Histoplasma capsulatum is "distributed worldwide, except in Antarctica, but most often associated with river valleys" [1] and occurs chiefly in the "Central and Eastern United States" [2] followed by "Central and South America, and ...
Primary pulmonary histoplasmosis is caused by inhalation of Histoplasma capsulatum spores, and approximately 10% of people with this acute infection develop erythema nodosum. [ 1 ] : 316 See also
Blastomycosis, also known as Gilchrist's disease, is a fungal infection, typically of the lungs, which can spread to brain, stomach, intestine and skin, where it appears as crusting purplish warty plaques with a roundish bumpy edge and central depression.
[1] [7] Systemic fungal infections are more serious and include cryptococcosis, histoplasmosis, pneumocystis pneumonia, aspergillosis and mucormycosis. [3] Signs and symptoms range widely. [3] There is usually a rash with superficial infection. [2] Fungal infection within the skin or under the skin may present with a lump and skin changes. [3]
Date: 8 May 2023, 20:15:28: Source: Own work: Author: Mikael Häggström, M.D. Author info - Reusing images - Conflicts of interest: None Mikael Häggström, M.D. Consent note: Consent from the patient or patient's relatives is regarded as redundant, because of absence of identifiable features (List of HIPAA identifiers) in the media and case information (See also HIPAA case reports guidance).
Histoplasmosis: Histoplasmosis can be diagnosed by samples containing the fungus taken from sputum (via bronchoalveolar lavage), blood, or infected organs. In the majority of immunocompetent individuals, histoplasmosis resolves without any treatment.
Histoplasma species have two forms: their environmental form is hyphal with microconidia and tuberculate macroconidia while their pathogenic form is a small intracellular yeast that exhibits narrow-necked budding [3] and no capsule.