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Rates of side effects appear to be higher than some groups of antibiotics such as cephalosporins but lower than others such as clindamycin. [7] Studies in other animals raise concerns regarding use in pregnancy. [8] No problems were identified, however, in the children of a small number of women who took the medication. [8]
Generally, oral or parenteral cephalosporins are recommended as the first-line agent for children older than two months. [45] [46] Second-line therapy should be considered for patients who have poor response to first-line treatment. Alternative choices include amoxicillin-clavulanate, nitrofurantoin, TMP/SMX, and ciprofloxacin. [44]
Common side effects include gastrointestinal effects such as nausea, vomiting, and diarrhea, as well as headache and insomnia. Postmarketing surveillance has revealed a variety of relatively rare but serious adverse effects associated with all members of the fluoroquinolone antibacterial class.
According to Forbes, there have been 45,000 reported cases of side effects related to fluoroquinolones. 23.1 million patients filled prescriptions for oral flouroquinolones in 2011.
Teeth discoloration and same side effects as tetracycline. Not to be given to children and pregnant or lactating women. Similar structure with tetracycline, but five times stronger, big volume distribution and long half-time in the body Tinidazole: Tindamax Fasigyn: Protozoal infections: Upset stomach, bitter taste, and itchiness: Trimethoprim(Bs)
Antibiotic synergy is desirable in a clinic sense for several reasons. At the patient level, the boosted antimicrobial potency provided by synergy allows the body to more rapidly clear infections, resulting in shorter courses of antibiotic therapy. [3] Shorter courses of therapy in turn reduce the effects of dose-related toxicity, if applicable ...
Amoxicillin may cause gastrointestinal discomfort, namely nausea and vomiting. [26] To eliminate these adverse effects, take the medication after a meal. Besides, this antibiotic may disrupt bowel microflora and induce diarrhea. [27] In rare cases, amoxicillin may induce risk of Clostridioides difficile-associated diarrhea. [26] [28]
Interactions between alcohol and certain antibiotics may occur and may cause side effects and decreased effectiveness of antibiotic therapy. [60] [61] While moderate alcohol consumption is unlikely to interfere with many common antibiotics, there are specific types of antibiotics with which alcohol consumption may cause serious side effects. [62]