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Lisinopril is a medication belonging to the drug class of angiotensin-converting enzyme (ACE) inhibitors and is used to treat hypertension (high blood pressure), heart failure, and heart attacks. [7] For high blood pressure it is usually a first-line treatment. It is also used to prevent kidney problems in people with diabetes mellitus. [7]
ACE inhibitors were initially approved for the treatment of hypertension and can be used alone or in combination with other anti-hypertensive medications. Later, they were found useful for other cardiovascular and kidney diseases [4] including: Acute myocardial infarction (heart attack) [5] Heart failure (left ventricular systolic dysfunction) [6]
The Anatomical Therapeutic Chemical Classification System for veterinary medicinal products (ATCvet) is used to classify veterinary drugs. ATCvet codes can be created by placing the letter Q in front of the ATC code of most human medications. For example, furosemide for veterinary use has the code Q C03CA01. Some codes are used exclusively for ...
Antihypertensive. Antihypertensives are a class of drugs that are used to treat hypertension (high blood pressure). [1] Antihypertensive therapy seeks to prevent the complications of high blood pressure, such as stroke, heart failure, kidney failure and myocardial infarction. Evidence suggests that reduction of the blood pressure by 5 mmHg can ...
Lisinopril/hydrochlorothiazide. Lisinopril/hydrochlorothiazide, sold under the brand name Zestoretic among others, is a fixed-dose combination medication used for the treatment of high blood pressure (hypertension). [2] It contains lisinopril, an ACE inhibitor, and hydrochlorothiazide, a diuretic. [2][3] Typically, it becomes an option once a ...
The discovery of an orally inactive peptide from snake venom established the important role of angiotensin converting enzyme (ACE) inhibitors in regulating blood pressure. This led to the development of captopril, the first ACE inhibitor. When the adverse effects of captopril became apparent new derivates were designed.
According to the biopharmaceutics Classification System (BCS) drug substances are classified to four classes upon their solubility and permeability: [1] Class I - high permeability, high solubility. Example: metoprolol, paracetamol [2] Those compounds are well absorbed and their absorption rate is usually higher than excretion.
Lisinopril/amlodipine, sold under the brand name Lisonorm among others, is a medication used to treat high blood pressure. [1] It is a combination of lisinopril an ACE inhibitor with amlodipine a calcium channel blocker. [1] It may be used when blood pressure is not well controlled with each of the two agents alone. [4] It is taken by mouth.