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Though articular cartilage damage is not life-threatening, it does strongly affect one's quality of life. Articular cartilage damage is often the cause of severe pain, knee swelling, substantial reduction in mobility and severe restrictions to one's activities. Over the last decades, however, research has focused on regenerating damaged joints.
Over time, this increased weight can accelerate cartilage wear-down and joint damage. ... early diagnosis of osteoarthritis is essential for managing symptoms and preventing further joint damage.
In older adults, the meniscus can be damaged following prolonged 'wear and tear'. Especially acute injuries (typically in younger, more active patients) can lead to displaced tears which can cause mechanical symptoms such as clicking, catching, or locking during motion of the joint. [1]
Each meniscus has an outer vascular zone (red-red zone), which has a good blood supply and healing potential as well as a central avascular zone (white-white zone), which has limited healing capability. [2] The medial meniscus is more prone to injury due to its firm attachment to the joint capsule and limited mobility.
Cartilage, the tissue cushioning the ends of bones, preventing bone-on-bone contact with movement ... As arthritis progresses, joint damage can get worse. This could lead to joint deformities or a ...
Autologous articular cartilage transfer from a non-weight-bearing area to the damaged area, called osteochondral autograft transfer system, is one possible procedure that is being studied. [140] When the missing cartilage is a focal defect, autologous chondrocyte implantation is also an option. [141]
Cartilage in the knee may begin to break down after sustained stress, leaving the bones of the knee rubbing against each other and resulting in osteoarthritis. [7] Nearly a third of US citizens are affected by osteoarthritis of the knee by age 70. [8] Obesity is a known and very significant risk factor for the development of osteoarthritis. [9]
Symptoms include pain, an audible cracking sound during injury, instability of the knee, and joint swelling. [1] Swelling generally appears within a couple of hours. [2] In approximately 50% of cases, other structures of the knee such as surrounding ligaments, cartilage, or meniscus are damaged. [1]