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Astressin-B is a nonselective corticotropin releasing hormone antagonist that reduces the synthesis of adrenocorticotropic hormone and cortisol. [1] It reduces the synthesis of adrenocorticotropic hormone and improves the sexual drive of rats under stressing conditions. [2] Astressin-B is able to delay the emptying of solid food in mice. [3]
Mercaptopurine (6-MP), sold under the brand name Purinethol among others, is a medication used for cancer and autoimmune diseases. [2] Specifically it is used to treat acute lymphocytic leukemia (ALL), acute promyelocytic leukemia (APL), Crohn's disease, and ulcerative colitis. [2] [3] For acute lymphocytic leukemia it is generally used with ...
A Corticotropin-releasing hormone antagonist (CRH antagonist) is a specific type of receptor antagonist that blocks the receptor sites for corticotropin-releasing hormone, also known as corticotropin-releasing factor (CRF), which synchronizes the behavioral, endocrine, autonomic, and immune responses to stress by controlling the hypothalamic-pituitary-adrenal axis (HPA axis). [1]
gastrointestinal cancers (diagnosis) Ascrinvacumab [12] mab: human: activin receptor-like kinase 1: cancer Aselizumab [24] mab: humanized: L-selectin (CD62L) severely injured patients Atezolizumab [25] Tecentriq: mab: humanized: PD-L1: Y: cancer Atidortoxumab [26] mab: human: Staphylococcus aureus alpha toxin: Atinumab [16] mab: human: RTN4 ...
Elacestrant was not McDonnell’s first attempt at bringing a breast cancer drug to market. In 1996, his lab developed a similar drug, etacstil, which was the first oral medication in this class ...
Last August, she revealed her diagnosis on her podcast, explaining that she “was diagnosed with high-grade DCIS with micro-invasion.” According to Breastcancer.org , DCIS “is breast cancer ...
AOH1996 is an experimental anticancer medication which acts as a small molecule inhibitor of proliferating cell nuclear antigen (PCNA) and is in Phase I clinical trials at City of Hope as of August 2023 for the treatment of solid tumors.
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