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The JAK-STAT system consists of three main components: (1) a receptor (green), which penetrates the cell membrane; (2) Janus kinase (JAK) (yellow), which is bound to the receptor, and; (3) Signal Transducer and Activator of Transcription (STAT) (blue), which carries the signal into the nucleus and DNA. The red dots are phosphates.
Jak II [a] is an action-adventure platformer third-person shooter video game developed by Naughty Dog and published by Sony Computer Entertainment for the PlayStation 2 in 2003. It is the second game of the Jak and Daxter series and a sequel to Jak and Daxter: The Precursor Legacy.
Janus kinase 2 (commonly called JAK2) is a non-receptor tyrosine kinase.It is a member of the Janus kinase family and has been implicated in signaling by members of the type II cytokine receptor family (e.g. interferon receptors), the GM-CSF receptor family (IL-3R, IL-5R and GM-CSF-R), the gp130 receptor family (e.g., IL-6R), and the single chain receptors (e.g. Epo-R, Tpo-R, GH-R, PRL-R).
[22] The soundtracks for Jak and Daxter: The Precursor Legacy, Jak II, Jak 3, and Jak X: Combat Racing were all commercially released in 2019 by Limited Run Games as part of the Collector's Edition of each respective game. [14] On November 2, 2009, Jak and Daxter: The Lost Frontier Original Soundtrack was released on the iTunes Store by SIE. [23]
Jak 2 may refer to: Jak II, a 2003 video game; JAK2, or Janus kinase 2, an enzyme This page was last edited on 5 January 2025, at 10:50 (UTC). Text is available ...
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Janus kinase (JAK) is a family of intracellular, non-receptor tyrosine kinases that transduce cytokine-mediated signals via the JAK-STAT pathway.They were initially named "just another kinase" 1 and 2 (since they were just two of many discoveries in a PCR-based screen of kinases), [1] but were ultimately published as "Janus kinase".
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