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The sublingual route may also be used for vaccines against various infectious diseases. Thus, preclinical studies have found that sublingual vaccines can be highly immunogenic and may protect against influenza virus [4] [5] and Helicobacter pylori, [6] but sublingual administration may also be used for vaccines against other infectious diseases.
The sublingual gland (glandula sublingualis) is a seromucous polystomatic exocrine gland. Located underneath the oral diaphragm ( diaphragma oris ), the sublingual gland is the smallest and most diffuse of the three major salivary glands of the oral cavity, with the other two being the submandibular and parotid .
Serous demilunes, also known as Crescents of Giannuzzi or Demilunes of Heidenhain, are cellular formations in the shape of a half-moon (hence the name "demilune") on the mixed submandibular and sublingual salivary glands. [1] Serous demilunes are the serous cells at the distal end of mucous acini, the secretory endpieces of certain salivary ...
Around 800 to 1,000 minor salivary glands are located throughout the oral cavity within the submucosa [12] of the oral mucosa in the tissue of the buccal, labial, and lingual mucosa, the soft palate, the lateral parts of the hard palate, and the floor of the mouth or between muscle fibers of the tongue. [13]
Sublingual and buccal medication administration is a way of giving someone medicine orally (by mouth). Sublingual administration is when medication is placed under the tongue to be absorbed by the body. The word "sublingual" means "under the tongue." Buccal administration involves placement of the drug between the gums and the cheek.
The oral mucosa is very thin underneath the tongue, and is underlain by a plexus of veins. The sublingual route takes advantage of the highly vascular quality of the oral cavity, and allows for the speedy application of medication into the cardiovascular system, bypassing the gastrointestinal tract.
Billy Bob Thornton is more than happy to play a foul-mouthed Santa (“Bad Santa”) or a high school football coach (“Friday Night Lights”) or a NASA scientist (“Armageddon”), but one ...
Similar in size, shape and thickness to a postage stamp, thin-film strips are typically designed for oral administration, with the user placing the strip on or under the tongue (sublingual) or along the inside of the cheek (buccal). These drug delivery options allow the medication to bypass the first pass metabolism thereby making the ...