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Lhermitte's sign may also appear during or following high-dose chemotherapy. [7] [8] Irradiation of the cervical spine may also evoke it as an early delayed radiation injury, which occurs within 4 months of radiation therapy. [citation needed] Delayed onset Lhermitte's sign has been reported following head and/or neck trauma.
The sign suggests a lesion of the dorsal columns of the cervical cord or of the caudal medulla, correlating significantly with cervical MRI abnormalities. [111] Between 25 and 40% of MS patients report having Lhermitte's sign during the course of their illness.
Leser-Trélat sign at Who Named It? sudden onset of multiple pruritic seborrheic keratoses: Levine's sign: Samuel A. Levine: cardiology: myocardial infarction: patient clenches fist over chest when asked to describe pain Lhermitte's sign: Jean Lhermitte: neurology: lesions of cervical cord dorsal columns or caudal medulla, MS, chemotherapy ...
In older patients, CCS most often occurs after acute hyperextension injury in an individual with long-standing cervical spondylosis.A slow, chronic cause in this age group is when the cord gets caught and squeezed between a posterior intervertebral disc herniation against the anterior cord and/or with posterior pressure on the cord from hypertrophy of the ligamentum flavum (Lhermitte's sign ...
There are over 2 million with MS around the world, but when Williams received his official diagnosis back in 1999, not much was known about the disease. ... Sign in. Mail. 24/7 Help. For premium ...
Hi, first sign of MS!” she said to the show’s creator Liz Feldman on Applegate and Jamie-Lynn Sigler’s MeSsy podcast, recalling a sequence in which her character Jen was running across a field.
Christina Applegate began experiencing the first symptoms of multiple sclerosis while filming the pilot for Dead to Me, long before she was diagnosed with the disease in 2021.. During the ...
[156] [157] [158] Both Lhermitte's sign and painful dysesthesias usually respond to treatment with carbamazepine, clonazepam, [159] or amitriptyline. [160] [161] Sativex is approved for treatment of pain in MS in different countries, but due to its derivation from cannabis, it is currently [when?] not available in others, such as the USA. [162]