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Triamcinolone commonly cause local side effects only. The undesirable effects may be oral mucosa changes that breaks the inner mouth mucosal layer. The damage in the mucosa may also cause redness and irritation on the application area. [4] In rare situations, systemic side effects may occur.
Serious side effects may include psychosis, increased risk of infections, adrenal suppression, and bronchospasm. [6] Use in pregnancy is generally safe. [7] It works by decreasing inflammation and immune system activity. [6] Triamcinolone was patented in 1956 and came into medical use in 1958. [8] It is available as a generic medication. [9]
It provides relatively immediate relief and is used before using oral prednisone. Oral and dental paste preparations are used for treating aphthous ulcers. As an intravitreal injection, triamcinolone acetonide has been used to treat various eye diseases and has been found useful in reducing macular edema. [17]
Triamcinolone hexacetonide (brand name Aristospan; also known as triamcinolone acetonide 21-tebutate) is a synthetic glucocorticoid corticosteroid. [ 3 ] [ 4 ] [ 5 ] It is on the World Health Organization's List of Essential Medicines .
Amlexanox 5% paste is well tolerated, [5] and is typically applied four times per day directly on the ulcers. [3] A 2011 review found it to be the most effective treatment of the eight treatments investigated for recurrent canker sores. [6] It is also used to treat ulcers associated with Behçet disease. [7]
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Xerostomia itself has many possible causes, but commonly the cause may be side effects of medications, or conditions such as Sjögren's syndrome. Conversely, conditions which cause drooling or sialorrhoea (excessive salivation) can cause angular cheilitis by creating a constant wet environment in the corners of the mouth.
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