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2. How to Pay the Lowest Price for Cialis & Tadalafil - AOL

   www.aol.com/lifestyle/pay-lowest-price-cialis...

   The price of generic tadalafil can vary based on the dosage, but most versions of generic tadalafil cost $10 to $13 per tablet. When used daily, generic tadalafil can be less than $3 per pill ($79 ...

3. Cialis Side Effects: What to Expect (& How to Avoid Them) - AOL

   www.aol.com/cialis-side-effects-expect-avoid...

   Remember, tadalafil 5-milligram side effects tend to be less severe than those experienced with 10- or 20-milligram dosages. Your provider may recommend adjusting your Cialis dosage if you’re ...

4. Tadalafil - Wikipedia

   en.wikipedia.org/wiki/Tadalafil

   Tadalafil is an annulated 2,5-diketopiperazine. [25] It is also a 1,2,3,4-tetrahydro-β-carboline. Tadalafil can be synthesized starting from (D)-tryptophan methyl ester and piperonal via a Pictet–Spengler reaction. This is followed by condensations with chloroacetyl chloride and methylamine to complete the diketopiperazine ring: [26]

5. Tadalafil: Your Ultimate Guide to Dosages, Side Effects & More

   www.aol.com/tadalafil-ultimate-guide-dosages...

   Tadalafil is available in several dosages, from a minimum dosage of 2.5mg (milligrams) all the way up to a 20mg per tablet, the maximum dose of tadalafil in 24 hours. Tadalafil 10mg: Typical ...

6. Vardenafil - Wikipedia

   en.wikipedia.org/wiki/Vardenafil

   Vardenafil's indications and contraindications are the same as with other PDE5 inhibitors; it is closely related in function to sildenafil citrate (Viagra) and tadalafil (Cialis). The difference between the vardenafil molecule and sildenafil citrate is a nitrogen atom's position and the change of sildenafil's piperazine ring methyl group to an ...

7. Icos - Wikipedia

   en.wikipedia.org/wiki/Icos

   In 1998, Icos formed a 50/50 joint venture with Indianapolis-based Eli Lilly (Lilly Icos LLC) to develop and commercialize tadalafil as Cialis. [11] The release of Cialis in the United States was delayed in April 2002 when the Food and Drug Administration (FDA) recommended that Icos perform more studies, improve labelling, and address ...