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Antidepressant discontinuation syndrome is a relatively new phenomenon, being identified and described from 1950s onwards, in parallel with discovery and introduction of modern antidepressant medications, with the first MAOIs, and TCAs introduced from the 1950s onwards and the first SSRIs from the 1980s onwards. [8]
Antidepressant discontinuation syndrome, also called antidepressant withdrawal syndrome, is a condition that can occur following the interruption, reduction, or discontinuation of antidepressant medication. [187] The symptoms may include flu-like symptoms, trouble sleeping, nausea, poor balance, sensory changes, and anxiety.
Antidepressant discontinuation syndrome (ADS) can cause a “brain zap” side effect after stopping Lexapro. Here’s what causes them, according to a psychiatrist. Mysterious 'Brain Zaps' Are ...
SSRI discontinuation syndrome has been reported when treatment is stopped. It includes sensory, and gastrointestinal symptoms, dizziness, lethargy, and sleep disturbances, as well as psychological symptoms such as anxiety/agitation, irritability, and poor concentration. [57] Electric shock-like sensations are typical for SSRI discontinuation. [58]
Sexual side effects. Some antidepressants, including commonly prescribed ones from the class known as SSRIs (selective serotonin reuptake inhibitors), can cause sexual side effects such as ...
[181] [182] Discontinuation effects appear to be less for fluoxetine, perhaps owing to its long half-life and the natural tapering effect associated with its slow clearance from the body. One strategy for minimizing SSRI discontinuation symptoms is to switch the patient to fluoxetine and then taper and discontinue the fluoxetine. [181]
Common side effects include dry mouth, nausea, feeling tired, dizziness, agitation, sexual problems, and increased sweating. [10] Severe side effects include an increased risk of suicide, serotonin syndrome, mania, and liver problems. [10] Antidepressant withdrawal syndrome may occur if stopped. [10]
Like other prescription drugs, antidepressants can come with side effects — a very common one being ED. While intimate problems can happen with any antidepressant drug, certain ones may be more ...