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The olfactory bulb is supported and protected by the cribriform plate of the ethmoid bone, which in mammals separates it from the olfactory epithelium, and which is perforated by olfactory nerve axons. The bulb is divided into two distinct structures: the main olfactory bulb and the accessory olfactory bulb.
These ORNs then project their axons to the olfactory bulb. In the olfactory bulb, the ORNs synapse with termination in the glomeruli. [6] Each glomerulus receives input from olfactory receptor neurons expressing only one type of olfactory receptor. The glomerular activation patterns within the olfactory bulb are thought to represent the quality ...
The Lady and the Unicorn, a Flemish tapestry depicting the sense of smell, 1484–1500. Musée national du Moyen Âge, Paris.. Early scientific study of the sense of smell includes the extensive doctoral dissertation of Eleanor Gamble, published in 1898, which compared olfactory to other stimulus modalities, and implied that smell had a lower intensity discrimination.
Human Olfactory bulbs and Olfactory tracts outlined in red. The olfactory system is a vital sense, and its dysfunction may lead to a reduced quality of life, an inability to determine hazardous odors, decreased pleasure in eating, and poor mental health. [32]
Likewise, there is no evidence for any accessory olfactory bulb in adult human beings, [48] and the key genes involved in VNO function in other mammals have pseudogenized in human beings. Therefore, while many debate the structure's presence in adult human beings, a review of the scientific literature by Tristram Wyatt concluded that on current ...
It supports the olfactory bulb, and is perforated by olfactory foramina for the passage of the olfactory nerves to the roof of the nasal cavity to convey smell to the brain. The foramina at the medial part of the groove allow the passage of the nerves to the upper part of the nasal septum while the foramina at the lateral part transmit the ...
The axons of OSNs expressing the same odorant receptors converge onto the same glomerulus at the olfactory bulb, allowing for the organization of olfactory information. An olfactory receptor neuron (ORN), also called an olfactory sensory neuron (OSN), is a sensory neuron within the olfactory system. [2]
The accessory olfactory system is the more recently evolved structure, first appearing in the common ancestor of modern amniotes and amphibians. The detection of non-volatile molecules and chemoreception seems to be the primary function of this system, as the accessory organ ( Jacobson's organ ) contains vomeronasal receptors responsible for ...