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Radiation-induced lung injury (RILI) is a general term for damage to the lungs as a result of exposure to ionizing radiation. [1] In general terms, such damage is divided into early inflammatory damage ( radiation pneumonitis ) and later complications of chronic scarring ( radiation fibrosis ).
Acute radiation syndrome (ARS), also known as radiation sickness or radiation poisoning, is a collection of health effects that are caused by being exposed to high amounts of ionizing radiation in a short period of time. [1] Symptoms can start within an hour of exposure, and can last for several months.
The proper treatment for cancer will likely include some combination of surgery, chemotherapy, radiation therapy, immunotherapy, hormone therapy, and targeted drug therapy. You may participate in ...
In the mammalian kidney, the regeneration of the tubular component following an acute injury is well known. Recently regeneration of the glomerulus has also been documented. Following an acute injury, the proximal tubule is damaged more, and the injured epithelial cells slough off the basement membrane of the nephron.
Radiation therapy (RT) is in itself painless, but has iatrogenic side effect risks. Many low-dose palliative treatments (for example, radiation therapy to bony metastases) cause minimal or no side effects, although short-term pain flare-up can be experienced in the days following treatment due to oedema compressing nerves in the treated area ...
Radiation fibrosis syndrome (also known as radiation fibrosis or radiation-induced fibrosis) is a human illness. It occurs as a result of cell death , and can be caused by radiotherapy . It is characterized by the accumulation of fibrin in irradiated tissues.
Cells have developed complex and efficient repair mechanisms to fix the lesions. In the case of free radical attack on DNA, base-excision repair is the repair mechanism used. Hydroxyl radical reactions with the deoxyribose sugar backbone are initiated by hydrogen abstraction from a deoxyribose carbon, and the predominant consequence is eventual ...
The repair model, instead of the target theory, emphasizes how a cell utilizes said cell’s repair mechanisms up to the limit of the cell’s repair machinery (the end of the shoulder). After the limit of the cell’s machinery is reached, the repair model generally notes that if any damage is left unhealed the dying process will be initiated.