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Researchers from the Mayo Clinic developed an animal model that involved mice receiving twice daily doses of minced pig brain tissue in saline intranasally. Biochemical testing indicated the signature autoantibodies (potassium channel antibodies, myelin basic protein antibodies and calcium channel antibodies) were present in experimental mice ...
Cellulitis is most often a clinical diagnosis, readily identified in many people by history and physical examination alone, with rapidly spreading areas of cutaneous swelling, redness, and heat, occasionally associated with inflammation of regional lymph nodes. While classically distinguished as a separate entity from erysipelas by spreading ...
The symptoms include poor balance and difficulty walking. Chronic cough and difficulty swallowing may also be present. Clinical findings include ataxia, sensory neuropathy, and absence of the vestibulo-ocular reflex. The syndrome was initially described in 2004. [1] In 2019, the cause was identified as biallelic pentanucleotide expansion in the ...
Erysipelas (/ ˌ ɛ r ə ˈ s ɪ p ə l ə s /) is a relatively common bacterial infection of the superficial layer of the skin (upper dermis), extending to the superficial lymphatic vessels within the skin, characterized by a raised, well-defined, tender, bright red rash, typically on the face or legs, but which can occur anywhere on the skin.
In its traditional manifestation, chronic inflammatory demyelinating polyneuropathy is characterized by symmetric, progressive limb weakness and sensory loss, which typically starts in the legs. Patients report having trouble getting out of a chair, walking, climbing stairs, and falling.
Neuritis (/ nj ʊəˈr aɪ t ɪ s /), from the Greek νεῦρον), [1] is inflammation of a nerve [2] or the general inflammation of the peripheral nervous system.Inflammation, and frequently concomitant demyelination, [3] [4] [5] cause impaired transmission of neural signals and leads to aberrant nerve function.
In immunology, systemic inflammatory response syndrome (SIRS) is an inflammatory state affecting the whole body. [1] It is the body's response to an infectious or noninfectious insult . Although the definition of SIRS refers to it as an "inflammatory" response, it actually has pro- and anti-inflammatory components.
Complex regional pain syndrome is a multifactorial disorder with clinical features of neurogenic inflammation (inflammation mediated by nerve cells), nociceptive sensitisation (which causes extreme sensitivity or allodynia), vasomotor dysfunction (blood flow problems which cause swelling and discolouration) and maladaptive neuroplasticity ...