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  2. Heterozygote advantage - Wikipedia

    en.wikipedia.org/wiki/Heterozygote_advantage

    A heterozygote advantage describes the case in which the heterozygous genotype has a higher relative fitness than either the homozygous dominant or homozygous recessive genotype. Loci exhibiting heterozygote advantage are a small minority of loci. [1] The specific case of heterozygote advantage due to a single locus is known as overdominance.

  3. Zygosity - Wikipedia

    en.wikipedia.org/wiki/Zygosity

    The words homozygous, heterozygous, and hemizygous are used to describe the genotype of a diploid organism at a single locus on the DNA. Homozygous describes a genotype consisting of two identical alleles at a given locus, heterozygous describes a genotype consisting of two different alleles at a locus, hemizygous describes a genotype consisting of only a single copy of a particular gene in an ...

  4. Genotype - Wikipedia

    en.wikipedia.org/wiki/Genotype

    In the example on the right, both parents are heterozygous, with a genotype of Bb. The offspring can inherit a dominant allele from each parent, making them homozygous with a genotype of BB. The offspring can inherit a dominant allele from one parent and a recessive allele from the other parent, making them heterozygous with a genotype of Bb.

  5. Major histocompatibility complex and sexual selection

    en.wikipedia.org/wiki/Major_histocompatibility...

    It is proposed that there is a chemo-attraction system responsible for the egg itself being able to discriminate and selectively choose between MHC-heterozygous and MHC-homozygous males. [34] Contrary to the Atlantic salmon and the Arctic char, red junglefowl Gallus gallus males instead of females exert cryptic preference. Male junglefowl ...

  6. Locus (genetics) - Wikipedia

    en.wikipedia.org/wiki/Locus_(genetics)

    Diploid and polyploid cells whose chromosomes have the same allele at a given locus are called homozygous with respect to that locus, while those that have different alleles at a given locus are called heterozygous. [3] The ordered list of loci known for a particular genome is called a gene map.

  7. Compound heterozygosity - Wikipedia

    en.wikipedia.org/wiki/Compound_heterozygosity

    In medical genetics, compound heterozygosity is the condition of having two or more heterogeneous recessive alleles at a particular locus that can cause genetic disease in a heterozygous state; that is, an organism is a compound heterozygote when it has two recessive alleles for the same gene, but with those two alleles being different from each other (for example, both alleles might be ...

  8. Underdominance - Wikipedia

    en.wikipedia.org/wiki/Underdominance

    In genetics, underdominance, also known as homozygote advantage, heterozygote disadvantage, or negative overdominance," [1] is the opposite of overdominance.It is the selection against the heterozygote, causing disruptive selection [2] and divergent genotypes.

  9. Test cross - Wikipedia

    en.wikipedia.org/wiki/Test_cross

    Under the law of dominance in genetics, an individual expressing a dominant phenotype could contain either two copies of the dominant allele (homozygous dominant) or one copy of each dominant and recessive allele (heterozygous dominant). [1] By performing a test cross, one can determine whether the individual is heterozygous or homozygous ...