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The endocannabinoid system, broadly speaking, includes: Endocannabinoids, which are the physiological ligands, or connecting substances, for the cannabinoid receptors.The main endocannabinoids are anandamide (N-arachidonoylethanolamide) and 2-AG (2-arachidonoylglycerol), which are in the same class of chemical compounds, called N-acylethanolamines (NAEs).
Cannabinoids (/ k ə ˈ n æ b ə n ɔɪ d z ˌ ˈ k æ n ə b ə n ɔɪ d z /) are compounds found in the cannabis plant or synthetic compounds that can interact with the endocannabinoid system. [1] [2] The most notable cannabinoid is the phytocannabinoid tetrahydrocannabinol (THC) (Delta-9-THC), the primary intoxicating compound in cannabis.
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The following is a list of antibiotics. The highest division between antibiotics is bactericidal and bacteriostatic. Bactericidals kill bacteria directly, whereas bacteriostatics prevent them from dividing. However, these classifications are based on laboratory behavior.
Narrow-spectrum antibiotics have low propensity to induce bacterial resistance and are less likely to disrupt the microbiome (normal microflora). [3] On the other hand, indiscriminate use of broad-spectrum antibiotics may not only induce the development of bacterial resistance and promote the emergency of multidrug-resistant organisms, but also cause off-target effects due to dysbiosis.
Antibiotics work by either killing bacteria directly or preventing their growth and spread. “Because if it can’t grow, it will die,” Hai Tran , clinical pharmacist and associate director of ...
Endocannabinoids serve as intercellular 'lipid messengers', [90] signaling molecules that are released from one cell and activating the cannabinoid receptors present on other nearby cells. Although in this intercellular signaling role they are similar to the well-known monoamine neurotransmitters such as dopamine , endocannabinoids differ in ...
While the most likely cellular targets and executors of the CB 2 receptor-mediated effects of endocannabinoids or synthetic agonists are the immune and immune-derived cells (e.g. leukocytes, various populations of T and B lymphocytes, monocytes/macrophages, dendritic cells, mast cells, microglia in the brain, Kupffer cells in the liver ...