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Each manufacturer assigns an ISI value (International Sensitivity Index) for any tissue factor they manufacture. The ISI value indicates how a particular batch of tissue factor compares to an international reference tissue factor. The ISI is usually between 0.94 and 1.4 for more sensitive and 2.0–3.0 for less sensitive thromboplastins. [5] [6 ...
PT reference varies between laboratory kits – INR is standardised INR: 0.9 [5] 1.2 [5] The INR is a corrected ratio of a patient's PT to normal Activated partial thromboplastin time (APTT) 18, [15] 30 [5] [18] 28, [15] 42, [5] 45 [18] s: Thrombin clotting time (TCT) 11: 18: s: Fibrinogen: 1.7, [15] 2.0 [5] 3.6, [5] 4.2 [15] g/L: Antithrombin ...
INR or Inr may refer to: Biology. Initiator element, a core promoter in genetics; International normalized ratio of prothrombin time of blood coagulation;
Bleeding time may be affected by platelet function, certain vascular disorders and von Willebrand Disease—not by other coagulation factors such as haemophilia.Diseases that may cause prolonged bleeding time include thrombocytopenia, disseminated intravascular coagulation (DIC), Bernard-Soulier disease, and Glanzmann's thrombasthenia.
The study was a prospective, randomized, non-blinded trial for which the patients were randomized into two groups, (i) weekly INR self-testing and (ii) monthly INR clinic-testing, using a stratified method of adaptive-allocation that was determined according to the duration of anti-coagulation and the indication for Warfarin. Although the study ...
The partial thromboplastin time (PTT), also known as the activated partial thromboplastin time (aPTT or APTT), is a blood test that characterizes coagulation of the blood.A historical name for this measure is the Kaolin-cephalin clotting time (KCCT), [1] reflecting kaolin and cephalin as materials historically used in the test.
In renal physiology, renal blood flow (RBF) is the volume of blood delivered to the kidneys per unit time. In humans, the kidneys together receive roughly 20 - 25% of cardiac output, amounting to 1.2 - 1.3 L/min in a healthy adult. [1]
In pharmacology, clearance is a pharmacokinetic parameter representing the efficiency of drug elimination. This is the rate of elimination of a substance divided by its concentration. [1]