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Psilocybin-containing mushrooms. Psilocybin therapy is the use of psilocybin (the psychoactive ingredient in psilocybin mushrooms) in treating a range of mental health conditions, such as depression, anxiety, addictions, [1] obsessive compulsive disorder (OCD), and psychosis. [2]
Psychotherapy is an effective treatment for trauma-related disorders. A meta-analysis of treatment outcomes has shown that 67% of patients who completed treatment for PTSD no longer met diagnostic criteria for PTSD. [4] For those seeking evidence-based psychotherapy treatment, it is estimated that 22-24% will drop out of their treatment.
The Phase 2 trials of these studies, conducted in the U.S., Canada, and Israel, consisted of 107 participants who had chronic, treatment-resistant PTSD, and had had PTSD for an average of 17.8 years. Out of the 107 participants, 61% no longer qualified for PTSD after three sessions of MDMA-assisted psychotherapy two months after the treatment.
This would be the first FDA panel of outside experts to review a potential new PTSD treatment in 25 years. PTSD is a disorder caused by very stressful events and can significantly disrupt patients ...
The panel overwhelmingly voted against the treatment, with the committee voting 9 to 2 that the human trials of MDMA for PTSD did not prove it was an effective therapy. The panel also voted 10 to ...
A phase III study indicated that MDMA-assisted therapy represents a potential breakthrough treatment for severe PTSD that merits expedited clinical evaluation. [17] Based on this study, MDMA-assisted psychotherapy was granted breakthrough therapy designation by the FDA, a designation that indicates that there is preliminary evidence that an intervention might offer a substantial improvement ...
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