enow.com Web Search

Search results

  1. Results from the WOW.Com Content Network
  2. Sequence alignment - Wikipedia

    en.wikipedia.org/wiki/Sequence_alignment

    In bioinformatics, a sequence alignment is a way of arranging the sequences of DNA, RNA, or protein to identify regions of similarity that may be a consequence of functional, structural, or evolutionary relationships between the sequences. [1] Aligned sequences of nucleotide or amino acid residues are typically represented as rows within a matrix.

  3. Multiple sequence alignment - Wikipedia

    en.wikipedia.org/wiki/Multiple_sequence_alignment

    Multiple sequence alignment (MSA) is the process or the result of sequence alignment of three or more biological sequences, generally protein, DNA, or RNA. These alignments are used to infer evolutionary relationships via phylogenetic analysis and can highlight homologous features between sequences.

  4. Sequence analysis - Wikipedia

    en.wikipedia.org/wiki/Sequence_analysis

    There are two main types of sequence alignment. Pair-wise sequence alignment only compares two sequences at a time and multiple sequence alignment compares many sequences. Two important algorithms for aligning pairs of sequences are the Needleman-Wunsch algorithm and the Smith-Waterman algorithm. Popular tools for sequence alignment include:

  5. BLOSUM - Wikipedia

    en.wikipedia.org/wiki/BLOSUM

    The most common sequence alignment for protein is to look for similarity between different sequences in order to infer function or establish evolutionary relationships. This helps researchers better understand the origin and function of genes through the nature of homology and conservation .

  6. Conserved sequence - Wikipedia

    en.wikipedia.org/wiki/Conserved_sequence

    Residues that are conserved across all sequences are highlighted in grey. Below each site (i.e., position) of the protein sequence alignment is a key denoting conserved sites (*), sites with conservative replacements (:), sites with semi-conservative replacements (.), and sites with non-conservative replacements ( ). [1]

  7. Gap penalty - Wikipedia

    en.wikipedia.org/wiki/Gap_penalty

    A Gap penalty is a method of scoring alignments of two or more sequences. When aligning sequences, introducing gaps in the sequences can allow an alignment algorithm to match more terms than a gap-less alignment can. However, minimizing gaps in an alignment is important to create a useful alignment.

  8. DNA annotation - Wikipedia

    en.wikipedia.org/wiki/DNA_annotation

    They play an important role in DNA replication and repair, transcriptional regulation, and viral infection. Binding site prediction involves the use of one of the following two methods: [49] Sequence similarity based methods. They consist in the identification of homologous sequences with known DNA binding sites, or by aligning them with query ...

  9. Consensus sequence - Wikipedia

    en.wikipedia.org/wiki/Consensus_sequence

    And it is not possible to write it as a single consensus sequence e.g. ACNCCA. An alternative method of representing a consensus sequence uses a sequence logo. This is a graphical representation of the consensus sequence, in which the size of a symbol is related to the frequency that a given nucleotide (or amino acid) occurs at a certain position.