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  2. Cocaine dependence - Wikipedia

    en.wikipedia.org/wiki/Cocaine_dependence

    Cocaine is a powerful stimulant known to make users feel energetic, cheerful, talkative, etc. In time, negative side effects include increased body temperature, irregular or rapid heart rate, high blood pressure, increased risk of heart attacks, strokes and even sudden death from cardiac arrest.

  3. Cocaine - Wikipedia

    en.wikipedia.org/wiki/Cocaine

    Cocaine is a central nervous system stimulant. [46] Its effects can last from 15 minutes to an hour. The duration of cocaine's effects depends on the amount taken and the route of administration. [47] Cocaine can be in the form of fine white powder and has a bitter taste.

  4. Substance-related disorder - Wikipedia

    en.wikipedia.org/wiki/Substance-related_disorder

    Substance use, also known as drug use, is a patterned use of a substance (drug) in which the user consumes the substance in amounts or with methods which are harmful to themselves or others. The drugs used are often associated with levels of substance intoxication that alter judgment, perception, attention and physical control, not related with ...

  5. Substance use disorder - Wikipedia

    en.wikipedia.org/wiki/Substance_use_disorder

    This also prevents the cocaine from crossing the blood–brain barrier, negating the euphoric high and rewarding effect of cocaine caused from stimulation of dopamine release in the mesolimbic reward pathway. The vaccine does not affect the user's "desire" for cocaine—only the physical effects of the drug. [70]

  6. Stimulant use disorder - Wikipedia

    en.wikipedia.org/wiki/Stimulant_use_disorder

    Stimulant use disorder is a type of substance use disorder where the use of stimulants caused clinically significant impairment or distress. It is defined in the DSM-5 as "the continued use of amphetamine-type substances, cocaine, or other stimulants leading to clinically significant impairment or distress, from mild to severe". [1]

  7. These before and after photos show the real effects of ... - AOL

    www.aol.com/news/2016-05-01-these-before-and...

    The main side effects heroin causes on appearance according to New Health Advisor are: Weight loss due to loss of appetite, or because a heroin abuser may not prioritize eating Painful abscesses ...

  8. Levamisole induced necrosis syndrome - Wikipedia

    en.wikipedia.org/wiki/Levamisole_Induced...

    Levamisole has become a common additive to illicit cocaine. It is thought to intensify the "high" by releasing dopamine in the brain, acts as a bulking agent, and is a difficult adulterant to recognize. Potential risks of levamisole-laced cocaine include neutropenia, agranulocytosis, arthralgias, retiform purpura, skin necrosis, and fever.

  9. Stimulant - Wikipedia

    en.wikipedia.org/wiki/Stimulant

    Cocaine is a stimulant but is not normally prescribed therapeutically for its stimulant properties, although it sees clinical use as a local anesthetic, in particular in ophthalmology. [153] Most cocaine use is recreational and its abuse potential is high (higher than amphetamine), and so its sale and possession are strictly controlled in most ...